27.11.2016 Views

Behavioral Science

Create successful ePaper yourself

Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.

96 Deja Review: <strong>Behavioral</strong> <strong>Science</strong><br />

Table 13.2 Other Antidepressants Indicated for the Treatment of Depression<br />

Generic Brand Mechanism Side<br />

Name Name of Action Effects Other<br />

Bupropion Wellbutrin Unknown, likely Seizures, Contraindicated<br />

Zyban (for via dopamine insomnia, in patients with<br />

smoking and headache, seizures,<br />

cessation) norepinephrine nausea, bulimia, and<br />

vomiting, anorexia<br />

constipation,<br />

and tremor<br />

Used to treat<br />

sexual side<br />

effects caused<br />

by SSRIs<br />

Mirtazapine Remeron Presynaptic alpha-2- Highly Agranulocytosis<br />

adrenergic sedating, in 0.1%<br />

antagonist (↑ ↑appetite, Also used to<br />

norepinephrine ↑weight ↓ nausea<br />

and serotonin)<br />

also potent<br />

antagonist of<br />

5-HT 2 and<br />

5-HT 3<br />

Trazodone Desyrel Weakly inhibits Highly Used as a<br />

serotonin sedating, sleeping aid<br />

reuptake<br />

orthostatic<br />

hypotension<br />

Postsynaptically Uncommon<br />

antagonizes but can<br />

5-HT 2<br />

cause<br />

priapism<br />

(painful<br />

erection)<br />

and<br />

arrhythmias<br />

Nefazodone Serzone Similar to Headache, FDA black-box<br />

trazodone dry mouth, warning due<br />

blurred to risk of liver<br />

vision, failure<br />

somnolence,<br />

and<br />

orthostatic<br />

hypotension

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!