Behavioral Science
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172 Deja Review: <strong>Behavioral</strong> <strong>Science</strong><br />
What is the biggest benefit of clozapine?<br />
What is the mechanism of action of the<br />
atypical antipsychotic risperidone?<br />
What are other side effects of<br />
antipsychotic therapy?<br />
What is the cause of amenorrhea<br />
in women taking antipsychotics?<br />
Which pharmacologic agents are used<br />
to treat acute mania associated with<br />
bipolar disorder?<br />
What agents are used for maintenance<br />
therapy in bipolar disorder?<br />
What are some of the side effects<br />
of lithium?<br />
It is efficacious for treatment. It is<br />
efficacious for resistant schizophrenia,<br />
though because of the side effects and<br />
monitoring it is never first line.<br />
It works by blocking both dopamine<br />
and serotonin receptors.<br />
Weight gain and metabolic syndrome<br />
Anticholinergic effects<br />
Antihistaminergic effects/sedation<br />
Amenorrhea<br />
Temperature dysregulation<br />
Neuroleptic malignant syndrome<br />
Blood dyscrasias<br />
Sexual dysfunction<br />
Dopamine receptor antagonism leading<br />
to elevated prolactin levels<br />
Lithium<br />
Atypical antipsychotics<br />
Valproic Acid (aka Depakote, valproate)<br />
Carbamazepine<br />
Benzodiazepines<br />
Lithium<br />
Valproic acid<br />
Carbamazepine<br />
Atypical antipsychotics<br />
Lamotrigine (Lamictal)<br />
Polyuria → acts as an antidiuretic<br />
hormone (ADH) antagonist to cause<br />
nephrogenic diabetes insipidus<br />
Tremor<br />
Hypothyroidism<br />
Weight gain<br />
Gastrointestinal effects (nausea,<br />
vomiting, diarrhea)<br />
Leukocytosis (high white blood<br />
cell count)<br />
Acne<br />
Note: Use of lithium requires close<br />
monitoring of serum levels.
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