Behavioral Science
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Psychopharmacology 169<br />
What are the names of commonly<br />
prescribed tricyclic antidepressants?<br />
Why are tricyclics used less often<br />
than SSRIs?<br />
What other syndrome are TCAs<br />
indicated for treating?<br />
What are common side effects<br />
of tricyclic antidepressants?<br />
What are the effects of TCA overdose?<br />
What is the most important clinical<br />
test in evaluating suspected tricyclic<br />
overdose?<br />
What is the treatment of acute tricyclic<br />
overdose?<br />
Which tricyclic antidepressants<br />
are known to have more anticholinergic<br />
effects?<br />
What are examples of other tertiary<br />
tricyclics antidepressants?<br />
Which tricyclic agent is the least<br />
sedating?<br />
Which tricyclic is prescribed for<br />
enuresis (bed-wetting)?<br />
Which tricyclic is classically prescribed<br />
for obsessive-compulsive disorder?<br />
Amitriptyline<br />
Clomipramine<br />
Doxepin<br />
Desipramine<br />
Imipramine<br />
Nortriptyline<br />
Side effects and potential for lethal<br />
overdose. They are still very efficacious<br />
medicines.<br />
Chronic and neuropathic pain<br />
Tricyclic antidepressants have<br />
anticholinergic effects including dry<br />
mouth, blurry vision, constipation,<br />
urinary retention, confusion, and<br />
memory deficits.<br />
Cardiac effects are the most<br />
dangerous—notably widened QRS,<br />
prolonged PR and QT intervals.<br />
Sedation, delirium, and anticholinergic<br />
effects may also be present.<br />
ECG<br />
IV Sodium Bicarbonate<br />
Tertiary tricyclics (eg, amitriptyline)<br />
Imipramine<br />
Doxepin<br />
Desipramine<br />
Imipramine<br />
Clomipramine<br />
Note: This is the most serotonin-specific<br />
tricyclic.
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