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Behavioral Science

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Sleep <strong>Science</strong> and Disorders 47<br />

In a person with sleep problems related<br />

to OSA, why might you avoid<br />

benzodiazepines?<br />

What are the three most common causes<br />

of a circadian rhythm sleep disorder?<br />

During which phase of sleep would<br />

you expect nightmares to occur in?<br />

What are the similarities between sleep<br />

terrors and sleepwalking?<br />

How could you clinically differentiate<br />

sleep terror from sleepwalking?<br />

What is the treatment of sleep terrors<br />

and sleepwalking?<br />

You risk further compromising the<br />

patient’s ventilation by respiratory<br />

depression.<br />

1. Delayed sleep phase—“night owls,”<br />

more common in adolescents and<br />

tends to improve with age<br />

2. Jet lag—typically resolves over<br />

several days<br />

3. Shift work—eg, working the<br />

night shift<br />

REM<br />

Both are more common in children and<br />

may involve semicomplex to complex<br />

motor behaviors. Patients tend to be<br />

amnestic for both and in adulthood they<br />

are equally prevalent in men and<br />

women (1% prevalence of sleep terrors<br />

and 2% prevalence of sleepwalking).<br />

Both occur in slow wave sleep.<br />

Sleep terror has strong component of<br />

autonomic arousal and fear, often<br />

beginning with a terrified scream, and a<br />

lesser element of semipurposeful motor<br />

behaviors. Sleepwalking has minimal<br />

autonomic arousal/fear and motor<br />

behaviors are usually more complex.<br />

Children will usually grow out of them.<br />

Benzodiazepines can be helpful for<br />

adults, as can scheduled awakenings<br />

and environmental control.<br />

OTHER SLEEP CHANGES<br />

What polysomnogram (PSG) findings<br />

are characteristic of major depression?<br />

Reduced slow wave sleep (less delta<br />

waves), frequent nighttime awakenings,<br />

increased sleep latency (time until<br />

falling asleep), short REM latency<br />

(REM cycle starts sooner than normal<br />

90 minutes onset), and early morning<br />

waking.<br />

Tip: Low serotonin is associated with<br />

depression; therefore you would expect<br />

reduced total sleep and slow wave sleep.

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