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Brian P. Jacob, David C. Chen, Bruce Ramshaw, Shirin Towfigh (eds.) - The SAGES Manual of Groin Pain-Springer International Publishing (2016)

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118<br />

J. Jamnagerwalla and H.H. Kim<br />

<strong>of</strong> the appendix testis may have a more insidious onset <strong>of</strong> pain over<br />

several days, with waxing and waning <strong>of</strong> pain levels. <strong>The</strong> “blue dot sign”<br />

<strong>of</strong> a palpable, infarcted appendix testis can be seen on exam in<br />

up to 21 % <strong>of</strong> patients [ 28 ]. Ultrasound can reliably identify torsion <strong>of</strong><br />

the appendix testis and differentiate it from testicular torsion [ 29 ].<br />

Treatment consists <strong>of</strong> rest and nonsteroidal anti-inflammatory drugs<br />

(NSAIDs).<br />

Acute Epididymitis Acute epididymitis is an inflammation <strong>of</strong> the<br />

epi didymis presenting acutely with pain and swelling. Objective findings<br />

<strong>of</strong> acute epididymitis include fever, scrotal erythema, leukocytosis on<br />

urinalysis, and positive urine culture. <strong>The</strong> pathophysiology is unclear but<br />

is thought to be secondary to retrograde flow <strong>of</strong> infection into the<br />

ejaculatory ducts [ 30 ]. In men under age 35 years, the most common<br />

etiology <strong>of</strong> acute epididymitis is sexually acquired Chlamydia trachomatis<br />

and Neisseria gonorrhoeae , while in men aged 35 years and over,<br />

the organisms that cause urinary tract infections (e.g., Gram-negative<br />

rods) are the predominant isolates [ 31 , 32 ]. Men presenting with possible<br />

acute epididymitis should have a midstream urine collection along with<br />

Gram stain <strong>of</strong> a urethral smear, although empiric treatment should begin<br />

at the time <strong>of</strong> initial evaluation. Treatment involves bed rest, scrotal<br />

support, NSAIDs, and antibiotics.<br />

Orchitis Isolated acute orchitis is relatively rare, as it usually occurs<br />

by local spread <strong>of</strong> infection from the epididymis. Isolated orchitis <strong>of</strong>ten<br />

has a viral cause, with mumps being the most common etiology. Mumps<br />

orchitis is characterized by painful testicular swelling 4–8 days after the<br />

appearance <strong>of</strong> parotitis [ 33 ]. Orchitis develops in 15–30 % <strong>of</strong> men with<br />

mumps. Mumps orchitis is not common before puberty [ 34 ]. Mumps<br />

orchitis is associated with reduced testicular size in up to half <strong>of</strong> patients<br />

and with semen analysis abnormalities in about 25 % [ 35 ]. Treatment is<br />

largely supportive.<br />

Nephrolithiasis Nephrolithiasis is a common urological problem,<br />

with lifetime prevalence <strong>of</strong> approximately 10 % in men [ 36 ]. Although<br />

the classic presentation includes flank pain and hematuria, a stone<br />

impacted in the distal third <strong>of</strong> the ureter can cause referred pain to the<br />

groin. A stone should be considered in a patient who has groin pain<br />

associated hematuria, flank pain, or a history <strong>of</strong> nephrolithiasis. A noncontrast<br />

helical computed tomography (CT) scan is the preferred imaging

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