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Brian P. Jacob, David C. Chen, Bruce Ramshaw, Shirin Towfigh (eds.) - The SAGES Manual of Groin Pain-Springer International Publishing (2016)

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12. Chronic Pelvic <strong>Pain</strong> in Women<br />

161<br />

reporting significant improvement in pain symptoms [ 17 ].<br />

Notwithstanding adequate trial design, these studies documented a 30 %<br />

placebo effect; the difference, however, was that the therapeutic benefit<br />

was much longer- lasting for those in the treatment arms [ 18 ].<br />

DIE is not consistently recognizable by the unfamiliar surgeon, and<br />

since depth <strong>of</strong> infiltration correlates with pain symptoms, excising these<br />

lesions seems more logical [ 19 ]. Ovarian endometrioma, <strong>of</strong>ten associated<br />

with DIE, are better managed by enucleating the cyst rather than<br />

ablation [ 20 , 21 ]. Data to support postoperative suppression are limited,<br />

although the benefits <strong>of</strong> surgery may be extended with combined oral<br />

contraceptives (COCs), progestins, or gonadotropin- releasing hormone<br />

agonists (GnRH-a).<br />

Adenomyosis<br />

Adenomyosis is an enigmatic disorder characterized anatomically as<br />

endometrial glands and stroma existing within the myometrium diffusely.<br />

Focal lesions are referred to as an adenomyoma . Although traditionally<br />

gynecologists have considered adenomyosis a cause <strong>of</strong> heavy,<br />

prolonged, and/or painful menses, it is apparent from studies <strong>of</strong> hysterectomy<br />

specimens for a spectrum <strong>of</strong> benign disorders that adenomyosis<br />

is an extremely common entity, found in approximately 25–65 % <strong>of</strong><br />

hysterectomy specimens.<br />

Until relatively recently, adenomyosis was something diagnosed<br />

based on clinical suspicion and confirmed only at the time <strong>of</strong> hysterectomy.<br />

Advances in uterine imaging have provided the clinician with the<br />

opportunity to diagnose this entity with reasonable accuracy. In the relatively<br />

small uterus, TVUS is an effective means <strong>of</strong> identifying adenomyosis,<br />

assuming adequate sonographer skill and real-time evaluation<br />

<strong>of</strong> the study, as opposed to review <strong>of</strong> still images [ 21 ]. Magnetic resonance<br />

imaging (MRI) may be an effective secondary tool used to confirm<br />

adenomyosis, especially when the uterus is large or associated with<br />

concomitant uterine myoma.<br />

<strong>The</strong> relationship between adenomyosis and abnormal uterine bleeding<br />

(AUB) or CPP remains unclear, in particular because many trials<br />

were performed to evaluate symptom reduction without performing a<br />

hysterectomy. <strong>The</strong> levonorgestrel intrauterine system (LNG-IUS) has<br />

proved to be more effective than other modalities in quality <strong>of</strong> life measures<br />

when compared to hysterectomy in a randomized trial [ 22 ].

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