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Brian P. Jacob, David C. Chen, Bruce Ramshaw, Shirin Towfigh (eds.) - The SAGES Manual of Groin Pain-Springer International Publishing (2016)

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20<br />

P. Vahedifar and E. Kamrava<br />

Table 3.1. Criteria for diagnosis <strong>of</strong> CRPS, per <strong>International</strong> Association for the<br />

Study <strong>of</strong> <strong>Pain</strong>.<br />

1. Continued pain that is disproportionate to the inciting event<br />

2. No other diagnosis better explains the signs and symptoms<br />

3. Signs and symptoms below<br />

Symptom (complaint) Sign (physical exam)<br />

Sensory<br />

Vasomotor<br />

Sudomotor/<br />

edema<br />

Motor/trophic<br />

At least 1 symptom in at<br />

least 3 <strong>of</strong> the following<br />

categories<br />

− Hyperesthesia<br />

− Allodynia<br />

− Temperature asymmetry<br />

− Skin color changes<br />

− Skin color asymmetry<br />

− Edema<br />

− Sweating changes<br />

− Sweating asymmetry<br />

− Decreased range <strong>of</strong><br />

motion<br />

− Motor dysfunction such<br />

as weakness, tremor,<br />

dystonia<br />

− Trophic changes such as<br />

hair, nail, or skin changes<br />

At least 1 sign at the time <strong>of</strong><br />

evaluation in at least 2 <strong>of</strong> the<br />

following categories<br />

− Hyperalgesia to pin prick<br />

− Allodynia to light touch<br />

− Allodynia to temperature<br />

sensation<br />

− Allodynia to deep somatic<br />

pressure<br />

− Allodynia to joint movement<br />

− Temperature asymmetry<br />

greater than 1 °C<br />

− Skin color changes<br />

− Skin color asymmetry<br />

− Edema<br />

− Sweating changes<br />

− Sweating asymmetry<br />

− Decreased range <strong>of</strong> motion<br />

− Motor dysfunction such as<br />

weakness, tremor, dystonia<br />

− Trophic changes such as<br />

hair, nail, or skin changes<br />

Adapted from Harden et al. [ 3 ], with kind permission John Wiley & Sons<br />

Pharmacologic Treatment<br />

Oral pharmacological treatment <strong>of</strong> CRPS has shown beneficial treatment<br />

with early-onset CRPS. <strong>The</strong> use <strong>of</strong> corticosteroids in early stages<br />

<strong>of</strong> CRPS has proven effective in some patients. Kozin et al. demonstrated<br />

that the pulsed use <strong>of</strong> steroids in patients with chronic regional<br />

pain syndrome showed improvement in 60–80 % <strong>of</strong> patients after<br />

2 weeks [ 7 ]. Similarly, Christensen et al. confirmed decrease in pain in<br />

the first 3–4 months [ 8 ]. Farah et al. have also shown effectiveness <strong>of</strong><br />

NSAIDS in some forms <strong>of</strong> CRPS in early stages <strong>of</strong> disease [ 9 ].

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