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Brian P. Jacob, David C. Chen, Bruce Ramshaw, Shirin Towfigh (eds.) - The SAGES Manual of Groin Pain-Springer International Publishing (2016)

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26. Chronic Orchialgia:<br />

Workup and Management<br />

Jamin V. Brahmbhatt , Ahmet Gudeloglu ,<br />

and Sijo J. Parekattil<br />

Introduction<br />

Chronic groin or scrotal content (inguinal canal, spermatic cord, testicular,<br />

scrotum) pain ( CGSCP ) is a common presenting problem for<br />

several specialists—emergency room, primary care, general surgeon,<br />

and urologists. It can be both acute and chronic in nature and can be<br />

managed with medical or surgical interventions. <strong>The</strong> pain can be unilateral<br />

or bilateral and intermittent or constant and lasts longer than 3<br />

months [ 1 , 2 ]. <strong>The</strong> pain can be idiopathic or caused by nerve irritation<br />

or hypersensitivity through vasectomy, hernia repair, sports injury,<br />

abdominal surgery, or any intervention that can irritate the genit<strong>of</strong>emoral<br />

or ilioinguinal nerves. Although the exact mechanism for CGSCP is not<br />

well understood, one common theme is a two-hit theory. <strong>The</strong>re is a baseline<br />

inflammatory or genetic process that leads to Wallerian degeneration<br />

<strong>of</strong> the peripheral nerves . In the groin or scrotum this degeneration<br />

may cause hypersensitivty <strong>of</strong> the ilioinguinal and genit<strong>of</strong>emoral nerves.<br />

A second inciting event—trauma, surgery, or irritation <strong>of</strong> these nerves—<br />

then leads to chronic neuropathic pain in this area (Fig. 26.1 ) [ 3 ].<br />

CGSCP may affect over 100,000 men annually [ 4 , 5 ]. Prevalence can<br />

range up to 33 % <strong>of</strong> men after vasectomy [ 6 ] and 63 % after inguinal<br />

hernia repair [ 7 – 9 ]. After hernia repair, the pain can be neuropathic or<br />

non-neuropathic secondary to mesh. Even with such a high prevalence<br />

after hernia repair, only 1 % <strong>of</strong> patients who suffer from CGSCP may be<br />

referred for further evaluation [ 10 ]. In this chapter we will review the<br />

current literature and present a structured algorithm for the evaluation<br />

and management <strong>of</strong> CGSCP.<br />

© <strong>Springer</strong> <strong>International</strong> <strong>Publishing</strong> Switzerland <strong>2016</strong><br />

B.P. <strong>Jacob</strong> et al. (<strong>eds</strong>.), <strong>The</strong> <strong>SAGES</strong> <strong>Manual</strong> <strong>of</strong> <strong>Groin</strong> <strong>Pain</strong>,<br />

DOI 10.1007/978-3-319-21587-7_26<br />

343

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