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Brian P. Jacob, David C. Chen, Bruce Ramshaw, Shirin Towfigh (eds.) - The SAGES Manual of Groin Pain-Springer International Publishing (2016)

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144<br />

M. Hibner and C. Coyne<br />

present among patients with other painful conditions, including pudendal<br />

nerve entrapment, endometriosis, and even inguinal hernia .<br />

<strong>Pain</strong>ful Bladder Syndrome/Interstitial Cystitis Symptoms <strong>of</strong> interstitial<br />

cystitis are primarily suprapubic discomfort associated with filling<br />

<strong>of</strong> the bladder, including frequency, urgency, and/or nocturia. <strong>The</strong>se<br />

symptoms overlap with that <strong>of</strong> pudendal neuralgia [ 12 ]. <strong>The</strong>re is pain<br />

relief with bladder emptying. Patients can also experience pain in the<br />

labia/scrotum, vagina, and clitoris/penis. Inflammation <strong>of</strong> the bladder<br />

may be incited by exogenous factors, including certain foods. On examination,<br />

the patient may demonstrate bladder tenderness. Cystoscopy<br />

with hydrodistention should be included as part <strong>of</strong> the workup. <strong>The</strong><br />

potassium chloride sensitivity test involves instillation <strong>of</strong> KCl into the<br />

bladder during cystoscopy. Eliciting pain is diagnostic <strong>of</strong>, though not<br />

specific to, interstitial cystitis and predictive <strong>of</strong> positive response to<br />

medical therapy for this disease. After this test, local anesthetic can be<br />

instilled in the bladder. Relief <strong>of</strong> pain with this anesthetic challenge test<br />

is also diagnostic.<br />

Vulvodynia <strong>The</strong> diagnosis <strong>of</strong> vulvodynia can be enigmatic. It is <strong>of</strong>ten<br />

chronic, and diagnosis and treatment are difficult, as no single variant<br />

exists. As the term denotes, patients suffer from pain <strong>of</strong> the vulva.<br />

This may involve the labia, vagina, and clitoris. It is <strong>of</strong>ten due to a dermatologic<br />

condition, but similar symptoms can be mimicked by pudendal<br />

neuralgia [ 13 ].<br />

Provoked Vestibulodynia This disease results in pain at the vulvar<br />

vestibule , also referred to as vulvar vestibulitis syndrome . Patients have<br />

a burning pain only upon entry to the vagina, such as with sexual intercourse.<br />

On examination, palpation with a Q-tip results in tenderness <strong>of</strong><br />

vestibule .<br />

Vaginismus This is a spasm <strong>of</strong> the muscles surrounding the vagina.<br />

It is typically elicited upon any insertion or penetration, similar to pelvic<br />

floor tension myalgia or levator syndrome. On pelvic examination, pelvic<br />

floor muscle spasms are obvious in response to digital examination.<br />

As explained prior, treatment <strong>of</strong> pelvic floor muscle spasms must be<br />

completed prior to initiating treatment for pudendal neuralgia.<br />

Endometriosis Endometriosis should be included in all diagnoses <strong>of</strong><br />

the pelvis among women. <strong>The</strong> pelvic pain is cyclical and typically in the<br />

lower abdomen. More severe cases may result in continuous pain.<br />

Hormonal therapy may help address the symptoms. Laparoscopy will<br />

confirm the diagnosis.

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