ets exposure, lung cancer - Legacy Tobacco Documents Library

More documents

Recommendations

Info

Involuntary Srnoking and Lung Cancer : A Case-Control Study' L.vnnncs Qarf)nktl,2 Oncar Auarbach,z and Lou Joub*rtz' 1.OSTqACT-In a casa-control study in A hospitals from 1671 to ta8`, taf cases of lunp cancer snd 402 tusas ol colon-rrctum qncar (the Gontrolsi w+re /Csnfifwd tn nonamoktnp woman AII casns and controls w.rs confvrr> .d by htstoloqic ryrvhw of ftio", and nonsmokinp status and axpoaurss wars wrnfs.d by sntsrrs.w Odds nt os (OR) sncnasrd with Incr .as,np numb .r of ciparanrs smoltso by the husband parttcutarly for cipanttss smokso at horna 't•na OR for wom4n whose huabandt tmohsd 20 or mora oiparnnas tt home was 2 tl (45ti4 contid.nca hmm t 13 . 3 .95) A ioqtsttc nsqrasa,on anatysn anow.d a significant poa+Uw trsnd of tncraas+np risk with incr.asQd .xpoaura to the husbands srnokiny at hCme contr0l}10 for age hospital soQioeconomic claas and y.ar of oiaqnovs Comparison of women class1l,rc1 by numper of hours Utposed a day to smo>
, 481 ()rrflnk .l, Auarbaoh, and Joub+ri verification of the smoking history ln a study of the histologic type of lung cancer in relation to asbestos exposure, 49 of 774 men and women with a discharge diagnosis of miaoscopically proved lung cancer were rccorded as nonsmokers in the hospital chart (10) . After review of hospital records, histologic sections, and interviews, only 10 nses retnatned who had died of primarv lung cancer and who had never smoked . One• half of the others had smoked at some time and, one•half the confirmed nonsmokers had a primary cancer other than that of the lung . lt is apparent, therefore, that more studies on involuntary smoking are needed, with parttcular attention giver, to obtaining microscopic proof of primary lung cancer and more detailed information about exposures to cigarette smoke, METHODS To have available enough subjects for a case-control study of involuntary smoking• we obtained access to the records of 4 hospitals-5 in New Jersey and I in Ohio . In each of these institutions, we identified all lung cancer cases in women recorded during 1971-81 . In 2 hospitals the cases were selected from the Tumor Registry ; in 1 hospital, they were selected from the surgical index in the pathology department~, and in the other hospitals, records from the pathology laboratory were checked against the medical records diagnostic discharge index No case was selected that had been diagnosed prior to 1971, Cases with cancer of the colon-rectum served as controls Colonrectum cancers have been shown in epidemiologic studies not to be related to cigarette smoking Charts then were located and reviewed Cases that were diagnosed clinically only or by cytology, or as sarcoma or lymphoma of the lung, were excluded Those that occurred in smokers (or ex-smokers), according to hospital records, also were set aside . Only those charts in which the patient was specified as a nonsmoker, or in which the smoking habit was not recorded, were further investigated . All the slides for these cases and controls were pulled from the files (an average of -15 slides/case) and were reviewed blind (by O . A .) . In a small sample, slides for cases and controls were reviewed a second time to check consistency of the findings . Another sample of slides for smokers with lung cancer, and for subjects with diagnoses of sites other than lung or colon-rectum, also were selected for histologic review and were mixed in with the slides of nonsmokers . If slides were missing or not available, or of too poor quality for accurate diagnosis, the blocks for the case were located and new slides were prepared An interview based on a standard questionnaire was obtained for all cases and controls, along with microscopic proof . The interview was with the woman if she were still alive or with next of kin if she had died . Seven interviewers did all the questioning, three did interviewing in all 4 hospitals . About three-quarters of the interviews were with the patient or with spouu or children . All other informants had known the sub . JNCI VOL 75, NO S . SErTEMI
Page 1 and 2:
28 Mar.95 RWA/BRA C :\DATA\ETS\REGI
Page 3 and 4:
http://legacy.library.ucsf.edu/tid/
Page 5 and 6:
II . Ba A } OU xo A] : 1993 . 11 .
Page 7 and 8:
Intr.oduction _ :'t 0 1 933 ?8_8 PH
Page 9 and 10:
Epidemioloaie Methodoloay, Fpi.demi
Page 11 and 12:
General's Report, the 1986 U .S . N
Page 13 and 14:
disease (bronchitis, pneumonia, ast
Page 15 and 16:
ETS, such as banning of smoking, ha
Page 17 and 18:
I 11/01/93 22 :38 1 301 983 3829 PH
Page 19 and 20:
Page 21 and 22:
11/01/93 22 :38 1 301 983 3828 PHIL
Page 23 and 24:
ItLGUt .wT0ttY TOxtO01aGY Ar+D ?Iiw
Page 25 and 26:
SlS :nt \ 's I m :nt :y ty tn M htt
Page 27 and 28:
Fontham rc mJ. (199I) Gas6nkd d d.
Page 29 and 30:
could metart:, the :hange ;tween ib
Page 31 and 32:
Lt)llrZ 1281 Made in West Germany M
Page 33 and 34:
Page 35 and 36:
Wu, et al ., 1985 USA not presented
Page 37 and 38:
Brownson, R .C ., Alavanja, M .C .R
Page 39 and 40:
groups . The case group included bo
Page 41 and 42:
iI ''wt•• *~aw'..rrr .-,~ ;r,r,
Page 43 and 44:
. 8so~nson N al . 19 . World Hcalth
Page 45 and 46:
Page 47 and 48:
Page 49 and 50:
Page 51 and 52:
Page 53 and 54:
Page 55 and 56: http://legacy.library.ucsf.edu/tid/
Page 67 and 68: c i.rVV !'S Ei'G(.ro(s http://legac
Page 69 and 70: 0 TAIILE 5.3 SPOUSE PAdAS • FENWI
Page 77 and 78: l http://legacy.library.ucsf.edu/ti
Page 83 and 84: Fontham, E .T .H ., Correa, P ., Wu
Page 85 and 86: the Fontham, et al ., study were ad
Page 87 and 88: *-qaIVI---I significant . Fontham,
Page 93 and 94: i-11 33 91 0 7e (0 a4-1 30) 0 76 (o
Page 95 and 96: I . q+ r . a-el +•.~, w•!L>.r.+
Page 97 and 98: )IV~ r VaV'~ iM+~eKNt~+~M ~.~ w w
Page 99 and 100: tYa'4 QMNy.nN s, LH( cMC . tM M6 rl
Page 101 and 102: 1W t ..st~~e+Irr+ ..e~ r .r .~ 4•
Page 103 and 104: Ui'1 ~ ~# f t tS#~ .~~~f~~~~xj~ A }
Page 105: Garfinkel, L . Auerbach, 0 ., and J
Page 109 and 110: 4" Garilnk .l, Autrrbach, and Joub.
Page 111 and 112: "$ f3arifnkel, Auerbach, and Joub .
Page 113 and 114: Janerich, D ., Thompson, W .D . Var
Page 115 and 116: t %ol ;:1 •o lo LL''%G Ca .NCEi<
Page 117 and 118: ~ ol )2! \o 10 LL'NG C .~'sCER t`D
Page 121 and 122: Lung Cancer in Nonsmokers OECtFFREY
Page 123 and 124: 1216 C.wcfn March 1 1984 vai . 33 T
Page 125 and 126: 1218 CANCER March 1 1984 va 53 our
Page 127 and 128: , 1220 GNCER March 1 1984 TaaLE 4 .
Page 133 and 134: CONTENTS Monday, Fcbruiry 19, 1990
Page 135 and 136: CONTENTS Tu :sday, Fcbruar} 2 0, 19
Page 137 and 138: Wednesdsy, February 21, 1990 Sesslo
Page 141 and 142: They coacluded that dicu.r~ $-ctrot
Page 143 and 144: GTS Z SdGZOZ tabl e 1 E viderrjioto
Page 145 and 146: 3ource : Pron ot al ., 1988 http://
Page 147 and 148: ~ UZSZSQGZOZ Exposed in Childhood :
Page 149 and 150: Table 7 . Power Calcuiation Odds Ra
Page 153 and 154: Cr.•C+ ...,-xC .y~. 1 . 15-S1 Pas
Page 155 and 156: Lrxl caucrsmaxj sow•rn .airrr 1 c
Page 157 and 158:
52 4! 7 .1 !,r .) : 7M Ile 1.u+t ts
Page 159 and 160:
Page 161 and 162:
J . .1 . Ltp . Cusw. canoer itn_ I(
Page 163 and 164:
scm L .C. « ai . greater tharl 1
Page 165 and 166:
KAo LGscai. kta= oaaoer . To s+e if
Page 167 and 168:
e w http://legacy.library.ucsf.edu/
Page 169 and 170:
`1t A P - ~n T t ~ I ~W = N J i .oS
Page 171 and 172:
f 166 PltlSimpllp[ripriCrtll ioCYNI
Page 173 and 174:
Page 175 and 176:
Page 177 and 178:
;.~.;,,. . .. _ . . _ _ it, J C,,,r
Page 179 and 180:
isk factoc of Interast and S the rs
Page 181 and 182:
s a a M.SSIVE SMOKING ANll SMUKING
Page 183 and 184:
t k http://legacy.library.ucsf.edu/
Page 185 and 186:
l http://legacy.library.ucsf.edu/ti
Page 187 and 188:
Shimizu, H ., Morishita, M ., Mizun
Page 189 and 190:
Page 191 and 192:
392 http://legacy.library.ucsf.edu/
Page 193 and 194:
394 li . Bhimisu .t al . places htt
Page 195 and 196:
Page 197 and 198:
Page 199 and 200:
I h 1 Environmental Tobacco Smoke a
Page 201 and 202:
1or both wfy aad adult years . Tis
Page 203 and 204:
i.diated thau the escivsion of adrs
Page 205 and 206:
Page 207 and 208:
Smoking and Other Risk Factors for
Page 209 and 210:
Smoking status TAtLE 2-Erporurr to
Page 211 and 212:
,.' interviewed was murr likell to
Page 213 and 214:
Wu-Williams, A .H ., Dai, X .D ., B
Page 215 and 216:
`a b - ~ .2 Yoo http://legacy.libra
Page 217 and 218:
tna /wt disrau T+bk Vl hsu RFU ol l
Page 219:
t aRected itnr4eErn famly memben wu
show all

ets exposure, lung cancer - Legacy Tobacco Documents Library

You also want an ePaper? Increase the reach of your titles

Delete template?

Save as template?