ets exposure, lung cancer - Legacy Tobacco Documents Library

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Is passive smoking an added risk factor for lung
cancer In Chinese women?
1-C, Koo' Ph .D . . J .H-C . Ho' M .D ., D .Sc ., F .R .C .P ., F .A .C .R .,
D . Saw' F .R .C .P .A ., M .R .R .C . Path .
6O".'rA%Mt N Co~iry M .liaw . U .lws+ry N Nons CAw4 N004 [wai
s if . ~ N .D . lw.uiot N frdisCOtr 6%d Owrslofa. QwM tIisalah Narwl . NF a{ Crws
s il. • N .D . l .a .uuu M Lh.t.a• Qwrn AisuaA Nrwul . Hw+[ KeRt
XD f.ma2s btnt eranwr Paients .W =0 k..ltk7 Lhuitt .mtr .l4 w.v ircs~
.itwed to ilsaiU7 snd euantJfr tl. r.rious aure. .I p.u .. seeokieq . ...ng
Chinas (emil . la Hong Koeg . F« tl+s evervmokas- p .ui .v se}osurs h.o
wa-tal roure.. (id .a .pre .u t. add u ebe{r ri.k . F.. tJ. .e•era+e .Ys.
,ualltaav . asaes.roenu (.n,olt Ga"urt euetvnr . ss. .Acn Fsui .e esptuee
tur+rd) . and qu+ociuti .e s.an .manu (bours . rasm inretuir7) she . .l r s:
Q+iresac ditfsnnco 1~sTw .en cbe tat . (or pci .nu .nd .onrrols . M.r•wvt .
Loes t .lscirt eti.W vut sto( rxtiaisd .iih ikither leveL of pusi•e sewking
for tLs r.a M s .c+mokvs . T)ius. svr ru,dinp .ould usea, to inliaate
tbac Faui .t smo{uru, ss u+ i .otsied f.nor . lid .oi lu .s ae 1r+lluence .n
(s=al . luni ancc isadsnss in Hona K. . .4 .
Recently, there has besn renewed dierussion
on the possibie etfeeu of passive
ssmokins on 1un= eaacer risk (5, s, 19) .
ta paviouw studies oa tht possibility of
incrmsed risk of lung cancer among wives/husbar-ts
trolr, tlleir smok ;af spou•
ses, the dau (2 . 9, 12, 16) were on]y bssed
en wbe :her the spouse smoked (yes/no)
witth no funher quslifiutions on whether
the smoker actua .lly staoked in the pre•
seace of the subject and for bas+r loaQ .
Whero t qusstifiation * was done (S,
17, 1i), it was bued on the eurrent spou•
se's smoking habits . lt !s weU known that
the eaxcinoYeoetic process of iateraal solid
csacers tuually begfns 20 or more yurs
beiore di.agaosis wben there might luve
besa no e.zposuss frorn the eurreat sour•
ee . Funhe :more . little account was taken
of et.anges ia stabking habits or marria .
re, or'the possibility of exposure from the
work eaviron:aeat. Some of tseu pto
Rsewi+tid lacuwry 14, tM+ .
• t. .bw e.pw .n Lr eevrian .iw.l/ Y . sru.
http://legacy.library.ucsf.edu/tid/wyk81f00/pdf
blerns were raised by Harnmond a .nd St•
likoff (11) but they have ytt to be ad•
dressed by epidestiological srudie .s tA dtte .
Chinese females in Hon= Kong hxve an
avera`e annust.i age•sund.ardized ineiden•
ee rate of 24 .1/100A00 tor lung cancer
(13) . This is aflong the highest rates for
woraen in the world . In order to etore
diroctly assess the possible role of passive
smoking ia lung cs .acer development, a
retrospective stvdy of 200 female lung
ancer patienu and 200 healthy district
controls wu brrua in 1911 . Hong Kong,
wit.h an average urban density of 2'I,000
inlubitinis per square kilometer, and I
sa' of average livinf space per person. is
one of the most densely populated atess
1a tbe world. It is, tturefore, an apprsr
priate place to test the passive smolcing
aetioiopal bypothesis .
P .rieats and -setbodi
Tl+ )00 lusi sanest }scenes sy6i .d wae htaes
tA. ." ir *u•s+aumc iausmseo @( t br .nuJs
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