ets exposure, lung cancer - Legacy Tobacco Documents Library

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836 THE 4EW ENGL,IND JOU0 .NA1 Or 1lLDICINE Lrpi G . 111110
of exposure also failed to exclude the null valut"
Garfinkcl et al„' using a difierent mcuure for durauon
of exposure (husband's smoking in the lut S and
25 years), found one si`nifiunt usoctstion among
the large number examined Exposure due to smoking
b% the spouse . cxpressed in tcrms of pack•yeat :
while the spouse Aas li%~ing with the subject, wu
Wund not to be sifnificantly associared with lunj can•
ttr . Using a comparable measure of exposure, Trichopoulot
et aJ 1 reported relattvelr large increuei in
riuk (treater than twofold) 1'erhaps our data do ssot
ahow that smoking b~ the spouse increased the tisk b .r
itsclf beuuse smoking by the spouse made up only
about one third of the subjecu' Iifetimc exposure
to cnvironmentaJ tobacco smoke It is aiso possibie
that phvncal circumstances and dtfTerences in studv
areu . the size of retJdences, vcntilation . and other
importan ; phveical aipecu of the ltvtng condition>,, u
well as social habits that alTect exposure within the
familv, will need to be measured and Inahied before
tbe diAerences in findings among the studies can be
eeconciJed
The evidence we ttpon lends further support to the
obsenation that passive smokunj ma% snerease the
risk of subsequent lung t :ancer, and it sut`esu that it
vta• be parTtcularh important to protect ehildren and
adolncents Gom thu environmentaJ hazard .
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Ma .fsaehusctu MedtcsJ Soorty
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