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ets exposure, lung cancer - Legacy Tobacco Documents Library

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kii-ome bias in our study . Lung <strong>cancer</strong> cases were not derived<br />

from general population but from the p,uientF of a limited number of hospitals .<br />

The proportion of adenoc,rrcinornn patient, in our aeries was ten percent larger as<br />

compured with that :n total <strong>lung</strong> <strong>cancer</strong> Itatieuts of this area The proportion of<br />

scluamons cell carcinoma shotced in npposite tendency (Kar,uaR a 1983) . We<br />

electPd the control ; from the same hospitals considering that both cases and<br />

controls in is Qnte hospital may have similar backgrounds . Hon-ecer . one of the<br />

hospttal uu-, a can, - Itn,Nital and we had to include many breast <strong>cancer</strong> patients<br />

in the controls For this re .t~on we compared the status of passive smoking among<br />

the brrivt <strong>cancer</strong> patients with that among other controls . but we found no<br />

difference . Futthermore, the risk of <strong>lung</strong> <strong>cancer</strong> for the survivors of <strong>cancer</strong> of the<br />

brew~t a,>_< not high when assessed by the data of a population-b,ued <strong>cancer</strong><br />

rrgistn (Takano and Okuno : personal communication) .<br />

Our study showed that the exposura to tobacco smoke from household<br />

members (i .e., mother or husband's father) could be associated with female <strong>lung</strong><br />

<strong>cancer</strong>. As the precise situation of passive smoking in the home or other places<br />

is still unclear, further studies are needed to clarify the significance of passive<br />

smoking in relation to the etiology of <strong>lung</strong> <strong>cancer</strong> in Japanese women .<br />

AtknowkdQments<br />

We are ftrnteful to Ms K Htrose of Aichi Cancer Center Reaerrth Institute and Ms . Y .<br />

T,tl::ihwhi of Tohoku University School of )ledicirte for their technical assutance . This<br />

atudy x aa supported by a Orantlin-Aid for Cancer Research from the )linistn of Health and<br />

Welfara ((',nsnt Number 57S )<br />

I) Al :itw, 8.. Kato . H:. k Blot. WJ . (1986) Passive anwlialt and lucsE canoer among<br />

Japanse romea L4rar . iiw .. K . d8W-4807 .<br />

2) dreslow, N .E. k Day, N .E. (1990) The analysis of ore-sotttrol audiea . In :<br />

Statistaos/ Yei" it Ca,Ker Rres>ti1 . Vol . I . IARC Scientific Publicatwns No . 32.<br />

laterrutional Aratcy (or 8tiarah on Cutaer . Lron .<br />

3) Breslow, N .E .. Ihy, N .E .. Halvonen. K .T .. Prentice, R.L. k Sabet. C. (197B)<br />

&timatioa of asaltipk telaeire ewl trJnctiocr in eate!»d eaar couuoi studies .lswee .<br />

J . B/iJcrwiot . . 1M, 299-J01 .<br />

4) Byers, T. k Graham, 8 . (1084) The tpidemio)oU of diet and canaer. In : Alrauar<br />

in C4rcrr Rneoral, Vol,11, trditad by G, Klein k S . Weinbous+e, Academic his,<br />

4riando-Fbrida, pp . 1-60 .<br />

S) CorreA, P ., Picl-le, LW, lroatham, E ., Lin . Y. k Haeasttl. W. (1pdJ) Pa:ioe

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