ets exposure, lung cancer - Legacy Tobacco Documents Library

l
The classifiation used in this study might be criticized
because some women married to ex•smokers could be
counted in the same exposure ategory as a woman
exposed to smoke up to the time of he~ftnal illness .
However, all patients who have gone through diagnosis
and rcreatment for lung cancer had some period of time
when they were not exposed to others' smoke, either
before or after treatment . We believe that the classification
we used was indicative of the "usual amount of
smobce to which the person was exposed ." To determine
the i:xperience of a"pure" nonexpoud group, 17 cases
and 56 controls in this study were identified who were not
expcned to the smoke of others during the last 5 years,
during the last 25 years, whose husbands never smoked at
home or elsewhere, and who never were exposed to smoke
in Kheir ehildhood . These cases and controls were
eompared with all other subjects The OR was 1 14 (CL :
0 .81 . 1 .59) .
In conclusion, we found an elevated risk of lung
cancer, ranging from 13 to 91%, in women exposed to the
smoke of others, although the increase was not statis•
ticall% significant . The women who were married to
smokers of 40 or more cigarettes a dav or who were
exposed to the smoke of at least 20 cigarettes a day at
horne showed a risk twice as high as that of women not
exposed at all . This result is consistent with the dose•
response risk of exposure to the husband's smoke shown
in some case-control studies (2, 3). A dose-response
reLationship was confirmed in a logistic regression
analvsEs . The lack of a relationship when exposure was
classified b% hours exposed to smoke of others map hale
occurred because this variable does not accurately mea•
sure intensity of exposure . There is no consistently
http://legacy.library.ucsf.edu/tid/wyk81f00/pdf
Inrolunt4ry lrrnoklnq and Lu" Cancor A4g
higher risk for certain age groups or by histologic types,
or by exposure at home or at work Exposure in other
areas carried a higher OR, but this finding is difficult to
interpret
!lEFEiiENCEB
(1) HIRAYA4A T . Non•unokmg wives of haw smokers havc a high
mk ot lung c .tuer A suudy from Japan !t Med J 1981 .
!>32 1 e s-185
(?) TR>anroE•t.0s D . KAUN-nstr A . SrAaRns LL ct al . Lung cancer
and pasttve smoking int J Cancer 1961 . 21 :1-4
(1) CoRREA P . FoN7HAw E . rIOCEl CW, in ut Passive unoktnR and
lung anar Lancer 1963, 2:59i-597
(I) GARrtwuL L. Time urmdi in IunS cancer morutity among
nonsmokers and a nou on pautve amoktn` JNCI 1981, 66
1061-1066
(S) DLAIAT GG. WYNDtR EL Lung eaneer in nonunoken . Cancer
1964, 5! 1214-1221
t4i SANoLta DP .EvtRsoN R6 wtuox AJ Pasuvestrsokrn6rnadult•
hood and ancer nsk Am J Eptdemtol 196$ 121 .37-48
(7) CH1r. WC, Fvr.c SC . Lung cancer in nonsmokers in Hong Kong
ln Grundmann E, ed t,.ancer campaign Vol 6 Cancer
eptdemtologN Stuttsart and tier, York Flscher VerlaE . 1982
199-202
tdl Koo LC . Ho JH .C . SAV, D Active and passive smoking among
Irmale lung nncer patients and controls in Hong Kong J Exp
Clin Cancer Res 19A3 4 .l6i-375 .
(91 FRIED40, GD PrTTtTI D9 6w,ot RD PretalenceRndcarTelatei
of passive smoJ