ets exposure, lung cancer - Legacy Tobacco Documents Library

tna /wt disrau
T+bk Vl hsu RFU ol lung noar usaeuted with tipe> ;1({
pnor chroruc lunt dtseases Lung dtseases that wen fsnt
durosed within thrcc mn of )unl l.aoerr dsaptotts fand a
eompanble urnr penod for controlst werz rscluded from Me
anal)s•s After ao)usunl for smokin=, htstory of any pnor
tunt dtseau was assocuted wtth a 5d5 . tncrqsed nsk I95M,
Cl E1 The excess was /reates : for prseumonta (RA
: ./) An Incrcascd nsk was (ound (or broochtas and,or
emphvtema . but the assoctauon was hmned to sqwmous oat
;tll caneen IRR 1 6) and nol found for adenocaranoma tRR
09)
v.e rnvesttjated whether risk of lung cancer varied aeeard•
tn/ to the fal ume following the dtarnosts of pnor lung
disease E.arlter drtetttoe of chrotuc bronchrtts•emphyxma
conveyed rreatrr ntk Relauvt to those wrtlt no tusrory o(
chrontc broncluus-emphysenu tAe RRs wers 1 .) . 1 .) . arsd
I 1 respauvely for condtuons detecud 4- 10 . 11 -20, and
:1 - vea .n brfort lung canm dta=rsosis On the othn hand .
the FtRs wcrc hi/ner for more rseen( dtagnoses of prxumonu
and TB T1x RRs wcrc :' ' 5 and I! respeetiveiy (or
pnru .monia and '- 1 . 1 ), and 1 . : for TB fnt delected 4- 10 .
11-20 and 2) + yean pnor lo lung aneer dtarnosu TTe
tkvated nsk assocured with TB du3nox4 4-10 ye•an pnor
to lung cancer was strntficant, it was obserred for both
squxmous oat cell canarn and adenoarnnoma of the lunjand
amon= non-smoken as well as smoken,
Famil, 7rutort oJT® asd cancn
we obsernd a stMhant 60' . (95',t CI 1 2-'s I i mertised
nsk assocuted with TB tn a househo{d member, wttb simtiar
nsks for squamous oat oell attcxn and adaooaraacvru
The familial aswcunon wa.t sax m srnoken and rsoosmoken,
and rrmamed unehanrrd after ad)usunl for
personal history of TB TTe risk assonated w•Ith family history
of TB mcrea,ised with decrrutn/ ar when the Indes
subyect wu first expo+ed After ad)usttnl for smoking .
exposures at are 30 cortfernd nsks of
1 .7 . 1 .5 and 1 . : whea compared to tbase with no houxhob
TB czposuls
Famlly history of lung as+zr in 6nt dep .c rtiatins_
rrponed by 4 .5' . of the ases . wu usoeuted with a a¢uficant
E0'. . (95•i. CI 1 .1-30) merusnj nsk TTM was ltttk
dtf'iercecr tn nsk by cell type or erook,tnl status Tbe risk of
lung eancrr was t.orne-whas hssher among thox witb a famtly
htttory of other ancen tRR IA : 95% Ci 1 .0-2 .01 . wsth the
esceu nsk bcinl hsther (or adenoearctaosiu (RR l .i) t3un
for squa.mous .oat cell ancen (RR 1 .1) .
.Nrrurnsa/ asd rtroaikrtf.r j.crnn
Tabk Vlf pre+enu nats o(lua4 atncer by .atiow mensuual
aad ttptoducuve f.ctott Tltre .ert littk or no assocveioa
with aF at tnenarebe, parity . hrsursrtomy. tpontaateua
abonion. prefnaxy rasah+z+t tn diffcult labau- assd we of
oral contracrpuves There .vas a saPu5eant 30'i. (91v. Ct
1 .2- 1 .1) snc7naed nsk asaoeiatad .ntb hissory ot mssa.rlude .
asid ca.+es tandbd to bart a tater aF at natun .J saeoopatssac
altbout.h the tretsd .ras wt sasooth
http://legacy.library.ucsf.edu/tid/wyk81f00/pdf
Ll'NG CANCEa AMONG WOMEN IN CHINA eR!
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