ets exposure, lung cancer - Legacy Tobacco Documents Library

KAo LGscai.
kta= oaaoer . To s+e if psuivs smokizg
.dds risk to active smokers, the risks for
4ht smokcrs (< 100 k ; tobacco or 14
µtk rrs .rs) witb low or sto passive ezpossum
(< 13,000 hours or 13 bouss/dsy a
3C nars) asd tbose smokin: sdmllar
amaus:u but witb bsavy passive smoke
scposures were compared Cfabie YIII) .
The same eomparison was applied also to
the besvy amokers (> 100 kg or 14 pack
?ears) . We found aot only ao iacsrase but
aa acYtul desrease it the risk for botb
ifgitt aad heavy emokers rritb heavy passive
ezposurs eompatrd to tbose with ao
or 1ow expdsure. There was oa]y an (ncreafe
in the risk related to the kvels of tbeir
own ciruetu consumption . This result
was also found by Correa at LL(3) .
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Disctinsioa
Ia t2t9s retrospettive study on the pos•
sible influence of passive ststoking on the
high iacidence of lung taaeer it Hong
Kong Chinese feaules, we have attempted
to identiS;+ and quantify various sources
and typa'of tobacco exposure among 200
patieats and 204 district controls . We have
Umited our dau prsseztation to show oaly
those facton r=levatt to the ittue of
passive smoklbt . AA more deu3led descripiSon
andn disctusion of active smokint as
212
http://legacy.library.ucsf.edu/tid/wyk81f00/pdf
a risk factar was presented alsewbere (is) .
The appareat lack of aa as :ociuton
betweea pascfvt smoking aad the " of
lun; nacer in our study may be due to
possIbilitiss whlcb ocruz because passive
amokinj msy be ody t ary Mrah esrri•
Dozen, whose affect may be coaosaled by
ot2ter factors that play a role fa a melti•
factorial and multisuge ardoloty. Among
the femaJe aeYSr•uaoksrs, lnts•rvaaint
factors mi=bt eause an ovessludowirit or
a protective effett (e{ . brnachial irrita•
t(on, dictary s ot betacamuae)
. These factors fn Hong Kaad are li•
kely to be ditfereat from those fn Japan
(12) . USA. (9, 16), or Grerce (17, 1f), and
this differr.ace may ezpiain our different
sesults . The possibiliry that the ; dose•re•
spatue cusve resembies a lotistic it shs•
pe . such that c there is a dose greater
than srra which produces zero rrspoase •
wu r•onsidered by Hasnmond and 5eii•
koff (11) and may be opiratits= bere .
Cen.isJy the lack of an iacrosed risk
for the active smoke :-s from passive tmokiag
. whicli was also found by Corrsa ct
ai . tS) . Would aex .= to support the poesibility
that the effecu of active smokLzg
or, tadeed, otlser taotars ytt to be iden•
eifled F=17y overshadowed ehc art ;ino•
`eaic acuon of passive sMoking .
This, however, does eot iirtply that passive
smoking is iabocuous, as It may con•
tr;bute an added risk of other respiratory,
and cardiovascular diseases (i, 14, 16) .
The possibility of other factors like diet,
previous Eistory of respiratory diseases,
occupationsl wtpostues, ase of istAalaau,
etc .• overshadovving or inhibiting the ef•
facts of passive smoking on the risk of
lung cancer among aever•smoked females
in Hong Kong and also the roles of these
factors in the arcinogenesis an beint
investigated.
It is hoped that more direct assessmestt
of passive smoking by other wor•
ksrs !n other areu ean shed atore light
oa the passive smoking eoatraversy .