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ets exposure, lung cancer - Legacy Tobacco Documents Library

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Kabat, G .C ., and Wynder, E .L ., "Lung Cancer in Nonsmokers," Cancer<br />

53(5) : 1214-1221, 1984 .<br />

In 1984, Kabat and Wynder published results of a case-<br />

control study of hospitalized individuals, mostly from New York<br />

City . A total of 25 male cases and 53 female cases and their -<br />

matched controls were included . The authors wrote :<br />

The plausibility of a role of passive<br />

inhalation in <strong>lung</strong> <strong>cancer</strong> can be questioned on<br />

several grounds . . .<br />

Cases do not differ from controls except for<br />

the greater <strong>exposure</strong> to cigarette smoke at<br />

work reported by male cases compared to male<br />

controls .<br />

The authors reported that 18 of 25 male cases versus 11<br />

of 25 controls reported being exposed to ETS in the workplace .<br />

This result was statistically significant at P = 0 .05 . The point<br />

estimate for workplace <strong>exposure</strong> of males was reported elsewhere as<br />

3 .27 (95o CI 1 .01-10 .6) . However, the authors' reported results<br />

for women are inconsistent with their conclusions on men ; 26 of 53<br />

female cases versus 31 of 53 controls (i .e ., fewer cases than<br />

controls) reported <strong>exposure</strong> in the workplace . This result, a point<br />

estimate of 0 .68 (95% CI 0 .32-1 .47), is not statistically<br />

significant .<br />

http://legacy.library.ucsf.edu/tid/wyk81f00/pdf

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