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ets exposure, lung cancer - Legacy Tobacco Documents Library

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disease (bronchitis, pneumonia, asthma) has been confirmed no !<br />

more than 50% of the time . In these studies the clinical (<br />

endpoints (i .e ., the symptoms and/or diseases addressed) were I<br />

usually obtained from questionnaires completed by the parents and<br />

were conf irmed by phys ician examination or medical reccr :;s less i<br />

than 200 of the time . r v<br />

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~ ,~,~•~dd r<br />

. ~i . . e ° ' As in the studies<br />

sof~ pre-sc o0 .1 chi r2n, these studies in older children<br />

inadequately considered potentially important confounding<br />

variables that could have influenced the outcome of a study,<br />

alone or in combination .<br />

Other Potential Health Effects of ETS<br />

Epidemiologic studies have also attempted to deterraine<br />

whether long-term <strong>exposure</strong> of adults to ETS is associated with<br />

adverse health effects other than <strong>lung</strong> <strong>cancer</strong> . In these studies,<br />

spousal smoking has usually served as the marker for ETS <strong>exposure</strong><br />

(again, without biologic verification) . To date, there are no<br />

consistent data to indicate that•such <strong>exposure</strong>s are asscciated<br />

with increased respiratory illness or impaired pulmonary<br />

function, exacerbation of the condition of individuals wi'th<br />

underlying <strong>lung</strong> disorders (such as emphysema or chronic<br />

obstructive <strong>lung</strong> disease) , increased risk of cardiovascus .ar<br />

disease, or increased risk of <strong>cancer</strong> at sites other than the<br />

luna .<br />

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Y 0 har for a def<br />

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(1~~ 11~y ~~b0 _minl durin Whi ch tobacco smoke<br />

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i'!as uJ<br />

~ i~ad<br />

yag iah co h , i r<br />

e<br />

co a ; ~; Acute smoke e ::posurq<br />

evokes responses of e, .~e, nose and throat discomfort, whic : apne~z•<br />

to be due to direct irritative effects of components in t ::bacco~<br />

sro :•ce, rather than an allergic reaction . These acute irritant<br />

responses, arhich are preventable by adequate ventilation (thus<br />

~<br />

reducing levels of <strong>exposure</strong>), do not anpear to produce lc :~g-teri<br />

effeccs or damage organs that are irritated .<br />

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http://legacy.library.ucsf.edu/tid/wyk81f00/pdf<br />

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