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NanoSafetyCluster - Compendium 2012 trade moulders who will not probably be able to readily get hold of this information. Moreover, these projects are very academic orientated thus, they don’t fully meets the SMEs needs. In addition, methodologies to assess the exposure and hazard aren’t standardized, so that the results of projects like Nanosafe are difficult to interpret and apply to other conditions. Thus, we aim to develop a best practices guide directly applicable in the nanocomposite industry. The current handbooks, guides and reports of research projects are not focused on specific nanoparticles used in the current industrial setting of the packaging industry, which can differ enormously from another industrial process involving the use of polymers and nanoparticles. At this stage, our solution is innovative due to the direct application of our members in particular SMEs and industrial settings, as well as providing valuable information to characterize the toxicological profile and potential risk of the new manufactured nanocomposites and also those placed on the market in the recent years. In relation to nanocomposite safety, the commercial manufacture of nanoparticles is relatively new, so that, there isn’t consensus in relation to the potential migration and release of the nanofillers employed on the nanocomposite industry. In this sense, taking into account physicochemical properties of the nanofillers employed, the possibility of migration is likely. Therefore, manufactures of nanocomposites, with special attention to those who manufacture food contact materials, must predict the potential migration in order to protect the consumer’s health and comply with the current regulation. At this stage, our proposal will study the aspects concerning the migration and release of nanoparticles in the polymeric matrix, providing the SMEs with scientific and valid data to select the less hazardous nanofillers or predict the potential release to the end user. After studying the existing solutions and emerging research, the consortium has concluded that the submitted project has a high innovative character and will enhance significantly the state-of-theart in the nanocomposite area. There is a demand that the current solutions are not able to meet, and the other research approaches are not focused in the specific field of the nanocomposite industry. Therefore we have an opportunity to exploit our innovative approach, including the achievement of the results in a reasonable period of time. On the other hand, due to the current lack of data in the nanotechnology area, mainly in relation to the adequacy of testing models and exposure measurements, we have conducted a complete contingency plan, including a detailed risk analysis and the contingency actions to guaranty the progress beyond the state of the art, ensuring that the project results will be addressed. 6 Impact The development of the NanoSafePACK project will have a remarkable impact on the European SME Community and their citizens, clearly identifiable due to the hundreds of applications of the nanocomposite materials every day and the hundreds of people who use them. It’s expected a direct impact in the packaging and polymer nanocomposite industry, helping the SME to develop new innovative materials, which provide the end users with new products tailored to their needs. On the other hand, the implementation of the project results will enable the SME Associations, their members and other SMEs across Europe minimise the health impact and environmental risk from the nanoparticles, providing the information to safely design, manufacture and market nanotechnology enable products. At the moment, much of the research and development work is concentrated on the development of innovative products, considering new properties that improve the final application, while ,at the same time, the safety of the product has been compromised at all stages of nano-products manufacturing, use and disposal. Overall market value will benefit from important consumer preferences toward safe and environmentally friendly products, which will support consumption of high-performance nanocomposites. 186 Compendium of Projects in the European NanoSafety Cluster
7 Directory Table 3 Directory of people involved in this project. First Name Last Name Affiliation Address e-mail Maricela Ventura Centro Español de Plásticos Enrique Granados, 101 08008, Barcelona, Spain A. Lozano Wouter Geurts Centro Español de Plásticos Enrique Granados, 101 European Plastic Converters Avenue de Cortenbergh, 71 Tina Autenrieth European Plastic Converters Avenue de Cortenbergh, 71 1000 Brussels - Belgium Ingrid Verschueren European Plastic Converters Avenue de Cortenbergh, 71 1000 Brussels - Belgium Isabel Ferreira de Costa The Portuguese Association of Plastic Industry Carlos Fito Packaging, Transport and logistics research center Riccardo Concu Packaging, Transport and logistics research center Carla Cots Packaging, Transport and logistics research center Steve Hankin Institute of Occupational Medicine Edificio Libersil - Torre B, Rua de S. José, 35 2ºC, 1150-321 Lisboa Albert Einstein, 1 CP.46.980 Paterna (Valencia) – Spain Albert Einstein, 1 CP.46.980 Paterna (Valencia) – Spain Albert Einstein, 1 CP.46.980 Paterna (Valencia) – Spain Research Park North / Riccarton UK-EH14 4AP Edinburgh United Kingdom Jose Luis Romero Tecni-Plasper, S.L. Pol. Ind. Font de la Parera. Bonaventura Aribau, s/n La Roca del Vallès (Santa Agnès de Malanyanes), Barcelona Spain Maria Pais Tecni-Plasper, S.L. Pol. Ind. Font de la Parera. Bonaventura Aribau, s/n La Roca del Vallès (Santa Agnès de Malanyanes), Barcelona Spain Lorenzo Calabri Tec Star , Srl TEC Star Srl Viale Europa, 40 41011 Campogalliano (MO) - Italy Leonardo Rettighieri Tec Star , Srl TEC Star Srl Viale Europa, 40 41011 Campogalliano (MO) - Italy NanoSafetyCluster - Compendium 2012 ventura@cep-inform.es alozano@cep-inform.es Wouter.geurts@eupc.org Tina.Autenrieth@eupc.org Ingrid.verschueren@eupc.org isabelfcosta@apip.pt cfito@itene.com ricardo.concu@itene.com cots@itene.com steve.hankin@iom-world.org JoseLuis.Romero@plasper.com maria.pais@plasper.com calabri@tec-eurolab.com rettighieri@tec-star.it Compendium of Projects in the European NanoSafety Cluster 187
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Compendium of Projects in the Europ
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EDITED BY Michael Riediker, PD Dr.s
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CONTENTS NanoSafetyCluster - Compen
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Project Acronym ENNSATOX ENPRA EURO
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Foreword NanoSafetyCluster - Compen
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ENNSATOX ENgineered Nanoparticle Im
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The biological membrane and its dep
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distinguishes between the interacti
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Figure 10. Schematic representation
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WP5: • Permeability of NPs in hyd
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NanoSafetyCluster - Compendium 2012
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ENPRA RISK ASSESSMENT OF ENGINEERED
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vitro findings with in vivo models;
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protocols with real biological samp
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and it was organised in the frame o
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First Name Last Name Affiliation Ad
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EURO-NanoTox European Center for Na
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silver nanoparticles, iron nanopart
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The core functions of the Center, h
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8 Directory Table 1 Directory of pe
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HINAMOX Health Impact of Engineered
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High Resolution Electron Microscopy
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integrated risk assessment. Integra
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powders: What is the difference in
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InLiveTox Intestinal, Liver and End
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- to develop and validate a novel m
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environments, IEEE Industrial Elect
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INSTANT Innovative Sensor for the f
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complementary research which will l
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7 Copyright NanoSafetyCluster - Com
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ITS-NANO Intelligent testing strate
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approach to conveying the appropria
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in the discussion. The integration
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MARINA MANAGING RISKS of NANOMATERI
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for risk analysis, these tools need
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environmental ENM toxicity, but tox
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propose it as a Method Validation F
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and SiO2-NM200 and NM203, and a SiO
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ModNanoTox Modelling nanoparticle t
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3) To model environmental exposure
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Nanodetector European Network on th
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measurement interval. Measurements
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5 Directory Table 1 Directory of pe
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NANODEVICE Novel Concepts, Methods,
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ENP in order to be sure of their sa
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4.3 Exploring the association betwe
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NanoFATE Nanoparticle Fate Assessme
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or proteins associated with particu
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sludge. Information on rates of slu
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The exposures to be conducted will
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NanoFATE progression beyond the “
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Timing, hosts and locations of (grouped) events of NanoImpactNet

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