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NanoSafetyCluster - Compendium 2012 SANOWORK partners will integrate with the activities within the NanoSafety Cluster through activities in the following areas: - pristine and modified ZrO2 NPs, polyamide and TiO2 nanofibers, TiO2 and Ag NPs and CNTs and their physicochemical (chemistry, crystal structure, size, shape, coating, surface charge etc.); - results on sound toxicological endpoints: 1) cell viability, including apoptosis, and mitochondrial activity; 2) induction/inhibition of pro-inflammatory cytokines and chemokines; 3) oxidative stress; 4) effects on unique cell function or cell –specific endpoints (e.g. 6 Exploitation and dissemination strategy The dissemination of the results of SANOWORK will be promoted at all levels. Dissemination activities will be defined by the Management Committee and implemented at the Scientific Committee level. The website will be created at the beginning of the project. In fact, it is assumed that the results will not only be interesting to the scientific community but also to a great number of SMEs that work with Nanotechnology and Material Recycling/Recovery solutions. The dedicated website will produce an extensive record of all publications and communications originated on the course of the project. It will consist of a public area, a registration area and a private area. Public area will contain general information on the project, useful links to the EC services, nanotechnology portals, etc., a download area for downloading project brochures, newsletter, and other useful material such as public deliverables, news for communication of events, workshops, conferences related to the project, and contacts to allow the website visitors to have a direct link to the Consortium. The registration area will allow every public user to upload personal data (name, affiliation, area of interest and email address) in order to participate in the project’s mailing list. The private area will be exclusively used by the Consortium for exchanging and sharing electronic data. The partners will be able to access the private area by using their own username and password. Finally, the interactions with relevant technology (e.g. nanotechnological and advanced materials) an environmental management platforms will allow the Consortium to widen the potential applications and the dissemination of the resultsThere are several major areas of Sanowork research activity, which are expected to generate new technology and may therefore generate new intellectual property opportunities and regard: • Design for safe and manufacturing NMs • Hazard characterization immune function, barrier properties, etc…); 5) particle uptake and translocation; 6) fibrogenicity; 7) genotoxicity and cell transformation; - results of worker exposure assessment plan; - COST/BENEFIT evaluation of proposed risk remediation tools; - insurance risk quantification of identified worker exposure scenarios. • Exposure characterization Industry has a vital interest that products are safe within current and future legislation. In particular the strategies proposed by SANOWORK project are integrated within specific industrial processing lines, all relevant and strategic for the companies involved. It is so evident that companies will be strongly interested to exploit the results of proposed design for safety and manufacturing strategies by promoting safe and sustainable NMs and processes. The new surface modified NMs and improved processes will be COST/BENEFIT evaluated and the technological break-through easily converted in commercial products, in accordance to IP rights. Other data produced by the project will be used as product documentation in order to provide to industrial stakeholders (customers, insurance companies, chemical industry association) the necessary scientific and technological information in terms of product characteristics as well as toxicological and exposure features. Another big exploitable advantage that industries can take by the project is given by the promotion of safe occupational exposure scenarios as requested by REACH, giving free resources to safeguard their workers’ health and safety. This expertise should be used internal in the Companies as well as a service in the external market for some Companies. The interests of academics/public/private bodies involved in NMs Occupational Health and Safety issues relies on the attempt to overcome the lack of information about novel formulations that could pose an immediate problem for hazard and risk assessment, considered in the early stages of a product development. In particular the development of proposed risk reduction tools beyond common state-of-the-art will be relevant for the scientific community as well as a framework for interdisciplinary developments of the design for safety strategies. Naturally, the dissemination of results by publishing in high impact factor journals and through the participation to the most important events promoted by NanoSafety Cluster will be another relevant exploitation interest of such organizations. 260 Compendium of Projects in the European NanoSafety Cluster
7 Directory Table 2 Directory of people involved in this project. NanoSafetyCluster - Compendium 2012 First Name Last Name Affiliation Address e-mail Anna Luisa Costa ISTEC-CNR (ISTEC) Via Granarolo, 64, 48018 Faenza, Italy Lang Tran INSTITUTE OF OCCUPATIONAL MEDICINE (IOM) Alexei Antipov PLASMACHEM PRODUKTIONS- UND HANDEL GMBH (PCHEM) Denisa Stránská ELMARCO SRO (ELMARCO) Karin Nordström Dyvelkov GEA PROCESS ENGINEERING AS (NIRO) Giovanni Baldi COLOROBBIA ITALIA SPA (COL) Matthias Voetz BAYER TECHNOLOGY SERVICES GMBH (BAYER) Dominique Fleury INSTITUT NATIONAL DE L ENVIRONNEMENT ET DES RISQUES INERIS (INERIS) Tofail Syed UNIVERSITY OF LIMERICK (UL) Enrico Bergamaschi UNIVERSITA’ DEGLI STUDI DI PARMA (UNIPR) Lucia Migliore UNIVERSITA’ DEGLI STUDI DI PISA (UNIPI) Socorro Vázquez-Campos ACONDICIONAMIENTO TARRASENSE ASSOCIACION (LEITAT) Giuseppe Castellet y Ballarà ISTITUTO NAZIONALE ASSICURAZIONE INFORTUNI SUL LAVORO (INAIL) Research Avenue North, Riccarton , 45, EH14 4AP, EDINBURGH, United Kingdom RUDOWER CHAUSSEE, 29, 12489,BERLIN, Germany Svárovská, 621, 46010, Liberec 10, Czech Republic GLADSAXEVEJ, 305, 2860, SOBORG, Denmark Via Pietramarina, 123, 50059, Sovigliana Vinci, Italy Build. E41, Kaiser-Wilhelm-Allee, 51368, LEVERKUSEN, Germany Parc Technologique Alata, 60550, VERNEUIL EN HALATTE, France NATIONAL TECHNOLOGICAL PARK, PLASSEY, LYMERICK, Ireland Via Antonio Gramsci, 14, 43100, Parma, Italy anna.costa@istec.cnr.it lang.tran@iom-world.org antipov@plasmachem.com denisa.stranska@elmarco.com karin.dyvelkov@geagroup.com baldig@colorobbia.it matthias.voetz@bayer.com dominique.fleury@ineris.fr Tofail.Syed@ul.ie enrico.bergamaschi@unipr.it Via S. Giuseppe, 22, 56126, Pisa, Italy l.migliore@geog.unipi.it PASSEIG 22 DE JULIOL, 218, 08221, TERRASSA, Spain Via Roberto Ferruzzi, 38/40, 00143, ROMA, Italy svazquez@leitat.org g.castellet@inail.it Compendium of Projects in the European NanoSafety Cluster 261
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Compendium of Projects in the Europ
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EDITED BY Michael Riediker, PD Dr.s
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CONTENTS NanoSafetyCluster - Compen
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Project Acronym ENNSATOX ENPRA EURO
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Foreword NanoSafetyCluster - Compen
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ENNSATOX ENgineered Nanoparticle Im
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The biological membrane and its dep
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distinguishes between the interacti
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Figure 10. Schematic representation
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WP5: • Permeability of NPs in hyd
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NanoSafetyCluster - Compendium 2012
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ENPRA RISK ASSESSMENT OF ENGINEERED
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vitro findings with in vivo models;
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protocols with real biological samp
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and it was organised in the frame o
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First Name Last Name Affiliation Ad
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EURO-NanoTox European Center for Na
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silver nanoparticles, iron nanopart
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The core functions of the Center, h
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8 Directory Table 1 Directory of pe
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HINAMOX Health Impact of Engineered
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High Resolution Electron Microscopy
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integrated risk assessment. Integra
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powders: What is the difference in
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InLiveTox Intestinal, Liver and End
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- to develop and validate a novel m
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environments, IEEE Industrial Elect
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INSTANT Innovative Sensor for the f
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complementary research which will l
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7 Copyright NanoSafetyCluster - Com
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ITS-NANO Intelligent testing strate
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approach to conveying the appropria
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in the discussion. The integration
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MARINA MANAGING RISKS of NANOMATERI
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for risk analysis, these tools need
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environmental ENM toxicity, but tox
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propose it as a Method Validation F
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and SiO2-NM200 and NM203, and a SiO
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ModNanoTox Modelling nanoparticle t
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3) To model environmental exposure
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Nanodetector European Network on th
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measurement interval. Measurements
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5 Directory Table 1 Directory of pe
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NANODEVICE Novel Concepts, Methods,
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ENP in order to be sure of their sa
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4.3 Exploring the association betwe
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NanoFATE Nanoparticle Fate Assessme
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or proteins associated with particu
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sludge. Information on rates of slu
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The exposures to be conducted will
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NanoFATE progression beyond the “
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Timing, hosts and locations of (grouped) events of NanoImpactNet

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