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Timing, hosts and locations of (grouped) events of NanoImpactNet

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Nanodetector<br />

European Network on the Health <strong>and</strong><br />

Environmental Impact <strong>of</strong> Nanomaterials<br />

NanoSafetyCluster - Compendium 2012<br />

Contract Agreement: in negotiation Website: http://www.nanodetector.eu.eu<br />

Coordinator: Vladimir Mirsky, Lausitz University <strong>of</strong> Applied Sciences, Senftenberg, Germany<br />

No. Beneficiary name Short name Country<br />

1 Lausitz University <strong>of</strong> Applied Sciences - Hochschule Lausitz LUAS Germany<br />

(2) Leibniz-Institut für Analytische Wissenschaften – ISAS- e. V. ISAS Germany<br />

3 Imperial College London ICL UK<br />

4 Fraunh<strong>of</strong>er-Institute for Biomedical Engineering IBMT Germany<br />

5 Hybrid Integrated Technologies (HIT) Ltd. HIT Czech. Rep.<br />

6 Phasis PHASIS Switzerl<strong>and</strong><br />

7 Mivitec GmbH MIVITEC Germany<br />

8 Optolita OPTOLITA Lithuania<br />

9 Upperton Ltd UPPERTON UK<br />

10 MBN Nanomaterialia S.p.A. MBN Italy<br />

Contents<br />

1 Summary ..................................................................................... 79<br />

2 Background ................................................................................ 79<br />

2.1. Plasmonic detection <strong>of</strong> single nanoparticles ......................... 79<br />

2.2 Quantification <strong>of</strong> nanoparticles .............................................. 80<br />

2.3 Identification <strong>of</strong> nanoparticles ................................................ 81<br />

1 Summary<br />

Project Duration: 1 May 2012 – 31 September 2015<br />

Project Funding: 2.968 Mio. EUR<br />

The project is based on the new experimental phenomenon<br />

discovered recently by a project partner: single subwavelengthsize<br />

objects give rise to optical signals in surface plasmon<br />

resonance microscopy. This provides a unique possibility for<br />

ultrasensitive on-line detection <strong>of</strong> engineered nanoparticles.<br />

Within the project a development <strong>of</strong> the device for detection <strong>of</strong><br />

nanoparticles <strong>and</strong> its application for a number <strong>of</strong> practically<br />

important tasks will be performed. The work includesthe<br />

development <strong>of</strong> theoretical description <strong>of</strong> the new effect,<br />

optimization <strong>of</strong> main components <strong>of</strong> plasmonic microscope,<br />

development <strong>of</strong> sophisticated s<strong>of</strong>tware for effective image<br />

analyses <strong>and</strong> isolation <strong>of</strong> nanoparticle signals from background<br />

optical signals <strong>and</strong> noise.<br />

Preliminary experiments demonstrated a possibility to use surface<br />

modification to distinguish different types <strong>of</strong> nanoparticles. This<br />

approach will be used in the project to identify <strong>of</strong> nanoparticles<br />

3 Objectives <strong>of</strong> the project............................................................. 81<br />

4 Workplan .................................................................................... 82<br />

5 Directory ..................................................................................... 83<br />

6 Copyright .................................................................................... 83<br />

<strong>and</strong> to achieve this, an array with different receptor groups will be<br />

formed, <strong>and</strong> pattern recognition algorithms will be applied.<br />

Measurements will be performed in aqueous media as well as in<br />

air. Inorganic, plastic <strong>and</strong> protein nanoparticles will be examined.<br />

At the final step <strong>of</strong> the project monitoring <strong>of</strong> nanoparticles in<br />

simple <strong>and</strong> complicated probes as well as for monitoring <strong>of</strong><br />

workplaces <strong>and</strong> waste during production <strong>of</strong> inorganic <strong>and</strong> protein<br />

nanoparticles <strong>and</strong> during aging <strong>of</strong> nanostructured materials will be<br />

performed.<br />

2 Background<br />

2.1. Plasmonic detection <strong>of</strong> single nanoparticles<br />

A recent experimental discovery made by a project partner forms<br />

the basis for the novel approach to nanoparticle diagnostics<br />

proposed here. The proposed detector relies on exploiting an until<br />

Compendium <strong>of</strong> Projects in the European NanoSafety Cluster 79

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