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LCS III - Konica Minolta Sensing Americas, Inc.

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Standard Operations<br />

5.5.1.4 Change the measuring range after a measurement<br />

5.5.2 Take a Pharm. Eur. color measurement<br />

Sign Description<br />

42<br />

1. Press the upper or lower limit of the bar graph (touch-sensitive<br />

area 5 or 6).<br />

2. Enter the new limit and press OK to confirm.<br />

Note: It is only possible to change the limits inside the measuring range of<br />

the color scale. It is not possible to extend the range, e.g. to Hazen 2000.<br />

The current result and all further measurements will be displayed<br />

with the new measuring range.<br />

The <strong>LCS</strong> <strong>III</strong> method of determining color in accordance with the<br />

European Pharmacopoeia (Ph.Eur) corresponds to the<br />

specifications in Chapter 2.2.2 of the pharmacopoeia "Degree of<br />

coloration of liquids ", in which a total of 37 color reference solutions<br />

(CRS) are defined for the hues yellow (Y1-Y7), greenish-yellow<br />

(GY1-GY7), brownish-yellow (BY1-BY7), brown (B1-B9) and red<br />

(R1-R7). Each color reference solution is unambiguously defined in<br />

the CIE Lab color space in terms of its brightness, hue and<br />

saturation.<br />

There are two ways of color matching of a sample with the Ph.Eur.<br />

system:<br />

• Automatic: The color of the solution is compared to the colors<br />

of the 37 color reference solutions. The identifier of the<br />

reference solution whose color is closest to that of the sample<br />

(i.e. the reference solution with the smallest color difference<br />

DE* to the sample) is displayed.<br />

• Specified scale: A scale is specified (e.g. BY). The identifier of<br />

the reference solution whose color is closest to that of the<br />

sample within the specified scale (i.e. the reference solution<br />

with the smallest color difference DE* to the sample within the<br />

specified scale) is displayed.<br />

If a scale is specified (e.g. BY scale), one of the following five signs<br />

is used to define the correlation between the measurement results<br />

and the scale (see Table 5).<br />

Table 5 Specified scale<br />

= equal The color number of the sample is equal to that of the reference solution<br />

< less The color number of the sample is less than that of the reference solution<br />

> greater The color number of the sample is greater than that of the reference solution<br />

between The color number of the sample is between those of two reference solutions<br />

->nearest<br />

The sample does not match any reference solution in this scale, but the indicated reference<br />

solution is nearest in color

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