Small Animal Clinical Pharmacology - CYF MEDICAL DISTRIBUTION

CHAPTER 10 ANTIPARASITIC DRUGS
Parasite*
Dirofilaria immitis (nem)
(d)
Thelazia callipaeda (nem)
(d,c)
T .californiensis (nem)
(d,c)
Toxocara canis (nem) (d)
Toxoplasma gondii (prot)
(c)
Central nervous system
Angiostrongylus
cantonensis (nem) (d)
Baylisascaris procyonis
(nem) (d)
Potential sources of
infection
Public health significance
Treatment options in
dogs and cats
IH (muscids) Signal Ivermectin, moxidectin (as
topical treatment)
Comments
Aberrant migration can
cause severe
intraocular
inflammation. See
Heart and
pulmonary artery
Physical removal of
worms is also
possible
IH (muscids) Signal Ivermectin Physical removal of
worms is also
possible
IH (snails – including giant
African snail, slugs), PH
(frogs, toads, freshwater
prawn, crabs)
Signal (Infection esp. via
consumption of raw
snails)
Clindamycin
(atovaquone)
Anthelmintic treatment
may increase host
death rate.
Aberrant migration.
See Small intestine
Chorioretinitis and
anterior uveitis. See
Polysystemic
Primary definitive hosts
are Rattus spp.
Cause of ascending
paresis and lumbar
hyperalgesia in dogs
Aberrant larval
migration
See Small intestine
D. immitis (nem) (d) Aberrant larval
migration. See Blood
Toxocara canis (nem) (d)
Aberrant migration.
See Small intestine
Acanthamoeba spp (prot)
(d)
Encephalitozoon cuniculi
(prot) (d,c)
Neospora caninum (prot)
( d)
Visceral Sarcocystis spp
(prot) (d,c)
Toxoplasma gondii (prot)
(d,c)
Trypanosoma spp (prot)
(d,c)
Cuterebra spp (esp.
fontinella) (fly) (d,c)
Water and soil borne
(ingestion and
inhalation)
Signal Amphotericin B,
ketoconazole,
sulfonamide +
trimethoprim
Cause cutaneous,
pulmonary and CNS
disease
See Urogenital system
See Polysystemic
Unknown Unknown Reported in rare cases
of CNS disease. See
Small intestine
See Polysystemic
See Blood
Aberrant migration
in CNS, commonly
in olfactory bulbs,
optic nerves and
cribriform plate. See
Skin
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