Small Animal Clinical Pharmacology - CYF MEDICAL DISTRIBUTION

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REFERENCES Canada For veterinary pharmaceutical products: Veterinary Drugs Directorate, Health Products and Food Branch, Health Canada Holland Cross Complex, Ground Floor, 14–11 Holland Avenue, Ottawa, Ontario K1A 0K9, Canada, Address Locator – 3000A Tel: 1-877-VET-REAC (1-877-838-7322) Fax: 1-613-946-1125 Email: pharmacovigilance-vet@hc-sc.gc.ca Website: www.hc-sc.gc.ca/dhp-mps/vet/adversreact-neg/index_e.html For veterinary biological products: Canadian Food Inspection Agency, Veterinary Biologics Section, 2 Constellation Crescent (Floor 8), Ottawa, Ontario K1A 0Y9, Canada Tel: 1-613-221-7566 Fax: 1-613-228-6612 Website: www.inspection.gc.ca/english/anima/vetbio/ info/vb315e.shtml For veterinary topical pesticide products: Director, Pest Management Regulatory Agency, 2250 Riverside Drive, Ottawa, Ontario K1A 0K9, Canada Tel: 1-800-267-6315; 1-613-736-3799 Website: www.pmra-arla.gc.ca/english/legis/aer-e.html New Zealand For veterinary pharmaceutical, biological and pesticide products: Agricultural Compounds and Veterinary Medicines (ACVM) Group, New Zealand Food Safety Authority, PO Box 2835, Wellington, New Zealand Tel: 04-463-2550 Fax: 04-463-2566 Website: www.nzfsa.govt.nz/acvm/publications/forms/ adrform.htm South Africa For suspected adverse reactions observed during use of a veterinary medicinal product: Department of <strong>Pharmacology</strong> and Toxicology, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort, South Africa Tel: 27-012-529-8239 Fax: 27-012-529-8304 Email: rgehring@op.up.ac.za Report form: www.nda.agric.za/act36/Stock Remedies. htm United Kingdom For veterinary pharmaceutical, biological and pesticide products: Department for Environment, Food and Rural Affairs (DEFRA), Veterinary Medicines Directorate, Suspected Adverse Reaction Surveillance Scheme, FREEPOST KT4503, Woodham Lane, New Haw, Addlestone, Surrey KT15 3BR, UK Tel: 44-01932-338427 Fax: 44-01932-336618 Website: www.vmd.gov.uk/General/Adverse/adverse. htm United States of America For veterinary pharmaceutical products: Center for Veterinary Medicine, ADE Reporting System, US Food and Drug Administration, 7500 Standish Place, Rockville, MD 20855-2773, USA Tel: 1-888-FDA-VETS Website: www.fda.gov/cvm/adetoc.htm For topically applied external pesticide products: Document Processing Desk-6(a)(2), Office of Pesticide Programs-7504P, US Environmental Protection Agency, Ariel Rios Building, 1200 Pennsylvania Avenue NW, Washington, DC 20460-0001, USA Tel: 1-800-858-PEST (1-800-858-7378) Website: www.epa.gov/pesticides/fifra6a2/ For veterinary biological products: Center for Veterinary Biologics, 510 South 17th Street, Suite 104, Ames, IA 50010, USA Tel: 515-232-5785; 1-800-752-6255 Fax: 515-232-7120 Email: cvb@aphis.usda.gov Website: www.aphis.usda.gov/vs/cvb/html/ adverseeventreport.html REFERENCES Day MJ 2006 Vaccine side effects: fact or fiction. Vet Microbiol 117: 51-58 Edwards DS, Henley WE, Ely ER, Wood JLN 2004 Vaccination and illhealth: a lack of temporal association and evidence of equivalence. Vaccine 22: 3270-3273 Edwards IR, Aronson JK 2000 Adverse drug reactions: definitions, diagnosis and management. Lancet 356: 1255-1259 Etmina M, Carleton B, Rochaon PA 2004 Quantifying adverse drug events. Are systematic reviews the answer? Drug Safety 27: 757-761 Kramer MS 1981 Difficulties in assessing the adverse effects of drugs. Br J Clin Pharmacol 11: 105S Martin RM, May M, Gunnell D 2005 Did intense adverse media publicity impact on prescribing of paroxetine and the notification of 57
CHAPTER 3 ADVERSE DRUG REACTIONS suspected adverse drug reactions? Analysis of routine databases, 2001–2004. Br J Clin Pharmacol 61: 224-228 Mealey KL 2006 Adverse drug reactions in herding-breed dogs: the role of p-glycoprotein. Comp Cont Ed 28: 23-33 Neff MW, Robertson KR, Wong AK et al 2004 Breed distribution and history of canine mdr1-1∆, a pharmacogenetic mutation that marks the emergence of breeds from the collie lineage. Proc Nat Acad Sci USA 101: 11725-11730 Robins AH, Weir M, Biersteker EM 1987 Attitudes to adverse drug reactions and their reporting among medical practitioners. S Afr Med J 72: 131 Schwab M, Eichelbaum M, Fromm MF 2003 Genetic polymorphisms of the human MDR1 drug transporter. Annu Rev Pharmacol Toxicol 43: 285-307 Weber JCP 1984 Epidemiology of adverse reactions to nonsteroidal antiinflammatory drugs. Adv Inflamm Res 6: 1-7 Wiebe V, Hamiltion P 2002 Fluoroquinolone-induced retinal degeneration in cats. JAVMA 221: 1568-1571 FURTHER READING Anderson JA, Adkinson F 1987 Allergic reactions to drugs and biological agents. JAMA 258: 2891 Boothe DM 1990 Drug therapy in cats: mechanisms and avoidance of adverse drug reactions. JAVMA 196: 1297 Bukowski JA, Wartenberg D 1996 Comparison of adverse drug reaction reporting in veterinary and human medicine. JAVMA 209: 40 Cribb AE 1989 Idiosyncratic reactions to sulfonamides in dogs. JAVMA 195: 1612 Davis LE 1984 Hypersensitivity reactions induced by antimicrobial drugs. JAVMA 185: 1131 Edwards IR 1987 Adverse drug reaction monitoring: the practicalities. Med Tox 2: 405 Hanley JA, Lippman-Hand A 1983 If nothing goes wrong, is everything all right? Interpreting zero numerators. JAMA 259: 1743-1745 Hill AB 1965 The environment and disease: association or causation? Proc Roy Soc Med 58: 295-300 Hoskins JD, Hubbert WT, Selig JO et al 1982 A questionnaire for the clinical assessment of veterinary adverse drug reactions. Cornell Vet 72: 3 Johnson JM 1992 Reasonable possibility: causality and postmarketing surveillance. Drug Inf J 26: 553 Ndiritu CG, Enos LR 1977 Adverse reactions to drugs in a veterinary hospital. JAVMA 171: 335 World Health Organization 2002 The importance of pharmacovigilance. Safety monitoring of medicinal products. World Health Organization, Geneva 58
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An imprint of Elsevier Limited © E
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CONTRIBUTORS Matthias J Kleinz Depa
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Dedication To Tom, Rosalind and Jim
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CHAPTER 1 PRINCIPLES OF CLINICAL PH
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CHAPTER 1 PRINCIPLES OF CLINICAL PH
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CHAPTER 5 ANESTHETIC AGENTS Central
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CHAPTER 5 ANESTHETIC AGENTS Table 5
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CHAPTER 5 ANESTHETIC AGENTS FURTHER
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CHAPTER 6 SEDATIVES ● noradrenali
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CHAPTER 6 SEDATIVES treatment, with
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CHAPTER 6 SEDATIVES Benzodiazepines
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CHAPTER 6 SEDATIVES It is not misci
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CHAPTER 6 SEDATIVES respectively. H
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CHAPTER 6 SEDATIVES Table 6.1 Sugge
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7 Behavior-modifying drugs Kersti S
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CHAPTER 7 BEHAVIOR-MODIFYING DRUGS
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8 Antibacterial drugs Jill E Maddis
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CHAPTER 8 ANTIBACTERIAL DRUGS phary
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CHAPTER 8 ANTIBACTERIAL DRUGS dose
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CHAPTER 8 ANTIBACTERIAL DRUGS Table
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CHAPTER 8 ANTIBACTERIAL DRUGS Bacte
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CHAPTER 8 ANTIBACTERIAL DRUGS lacta
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CHAPTER 8 ANTIBACTERIAL DRUGS Antis
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CHAPTER 8 ANTIBACTERIAL DRUGS intri
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CHAPTER 8 ANTIBACTERIAL DRUGS inter
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CHAPTER 8 ANTIBACTERIAL DRUGS Teico
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CHAPTER 8 ANTIBACTERIAL DRUGS Diffe
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CHAPTER 8 ANTIBACTERIAL DRUGS forms
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CHAPTER 8 ANTIBACTERIAL DRUGS ● I
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CHAPTER 8 ANTIBACTERIAL DRUGS ● R
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CHAPTER 8 ANTIBACTERIAL DRUGS RIFAM
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9 Systemic antifungal therapy Josep
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CHAPTER 9 SYSTEMIC ANTIFUNGAL THERA
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10 Antiparasitic drugs Stephen W Pa
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CHAPTER 10 ANTIPARASITIC DRUGS ●
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CHAPTER 10 ANTIPARASITIC DRUGS Tabl
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CHAPTER 10 ANTIPARASITIC DRUGS leva
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CHAPTER 10 ANTIPARASITIC DRUGS ●
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CHAPTER 10 ANTIPARASITIC DRUGS Adve
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CHAPTER 10 ANTIPARASITIC DRUGS Mech
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CHAPTER 10 ANTIPARASITIC DRUGS Form
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CHAPTER 10 ANTIPARASITIC DRUGS prod
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CHAPTER 10 ANTIPARASITIC DRUGS Adve
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CHAPTER 10 ANTIPARASITIC DRUGS 62.5
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CHAPTER 10 ANTIPARASITIC DRUGS incr
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CHAPTER 10 ANTIPARASITIC DRUGS The
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CHAPTER 10 ANTIPARASITIC DRUGS func
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CHAPTER 10 ANTIPARASITIC DRUGS Para
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CHAPTER 11 GLUCOCORTICOSTEROIDS AND
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12 Immunomodulatory therapy Michael
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CHAPTER 12 IMMUNOMODULATORY THERAPY
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CHAPTER 13 NONSTEROIDAL ANTI-INFLAM
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CHAPTER 14 OPIOID ANALGESICS inflam
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A Agonist opioid (morphine) B Parti
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CHAPTER 14 OPIOID ANALGESICS admini
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CHAPTER 14 OPIOID ANALGESICS may ac
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CHAPTER 14 OPIOID ANALGESICS Small
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CHAPTER 14 OPIOID ANALGESICS Clinic
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CHAPTER 14 OPIOID ANALGESICS Contra
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CHAPTER 14 OPIOID ANALGESICS respon
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CHAPTER 14 OPIOID ANALGESICS Advers
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CHAPTER 14 OPIOID ANALGESICS Advers
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15 Cancer chemotherapy Jane M Dobso
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CHAPTER 15 CANCER CHEMOTHERAPY to m
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CHAPTER 15 CANCER CHEMOTHERAPY curr
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CHAPTER 15 CANCER CHEMOTHERAPY Tabl
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CHAPTER 15 CANCER CHEMOTHERAPY Clin
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CHAPTER 15 CANCER CHEMOTHERAPY sion
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CHAPTER 15 CANCER CHEMOTHERAPY In t
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CHAPTER 15 CANCER CHEMOTHERAPY afte
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CHAPTER 15 CANCER CHEMOTHERAPY Phar
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CHAPTER 15 CANCER CHEMOTHERAPY Form
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CHAPTER 15 CANCER CHEMOTHERAPY conc
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CHAPTER 15 CANCER CHEMOTHERAPY Phar
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CHAPTER 15 CANCER CHEMOTHERAPY best
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CHAPTER 15 CANCER CHEMOTHERAPY Form
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CHAPTER 15 CANCER CHEMOTHERAPY D-MA
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CHAPTER 16 ANTICONVULSANT DRUGS sei
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CHAPTER 16 ANTICONVULSANT DRUGS bit
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CHAPTER 16 ANTICONVULSANT DRUGS Kno
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CHAPTER 16 ANTICONVULSANT DRUGS exc
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17 Drugs used in the management of
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CHAPTER 17 DRUGS USED IN THE MANAGE
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CHAPTER 19 GASTROINTESTINAL DRUGS C
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CHAPTER 19 GASTROINTESTINAL DRUGS r
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CHAPTER 19 GASTROINTESTINAL DRUGS
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CHAPTER 19 GASTROINTESTINAL DRUGS
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CHAPTER 21 DRUGS USED IN THE TREATM
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23 Drugs and reproduction Philip G
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CHAPTER 23 DRUGS AND REPRODUCTION I
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CHAPTER 23 DRUGS AND REPRODUCTION F
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CHAPTER 23 DRUGS AND REPRODUCTION C
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CHAPTER 23 DRUGS AND REPRODUCTION M
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CHAPTER 23 DRUGS AND REPRODUCTION n
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CHAPTER 23 DRUGS AND REPRODUCTION E
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24 Topical dermatological therapy R
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CHAPTER 24 TOPICAL DERMATOLOGICAL T
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CHAPTER 25 OCULAR CLINICAL PHARMACO
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Index A α-adrenergic receptors 70,
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INDEX Antiplatelet drugs 456-457 pi
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INDEX Ceftazidime 168 Ceftiofur 166
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INDEX Drug receptors 4-8 Drug-drug
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INDEX Hepatic excretion 33 Hepatic
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INDEX Metabolism dogs vs cats 47 an
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INDEX Pentazocine 319, 327 Pentobar
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INDEX Semicarbazone 230 Septic arth
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