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Segmentation of 3D Tubular Tree Structures in Medical Images ...

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94 Chapter 5. Liver Vascular <strong>Tree</strong> <strong>Segmentation</strong><br />

ven vessel trees on cl<strong>in</strong>ical CT datasets (Section 5.3.2) and compared it to other methods<br />

with similar objectives (Section 5.3.3). The method performs well and produced only a<br />

few m<strong>in</strong>or errors without cl<strong>in</strong>ical significance, contrary to the other methods. In particular,<br />

the structural group<strong>in</strong>g and l<strong>in</strong>kage with the <strong>in</strong>corporated flow direction <strong>in</strong>formation<br />

was an important factor <strong>in</strong> obta<strong>in</strong><strong>in</strong>g the correct structure <strong>of</strong> multiple overlapp<strong>in</strong>g (vessel)<br />

trees (Sections 5.3.2, 5.3.3, and 3.4.1)<br />

<strong>Segmentation</strong> accuracy: On phantom datasets we quantified the segmentation accuracy<br />

for tubular objects with different radius under vary<strong>in</strong>g imag<strong>in</strong>g conditions (Section<br />

5.3.1). Investigated contrasts and scan resolutions showed almost no effect on the<br />

accuracy <strong>in</strong> case <strong>of</strong> vessels with larger diameter. For th<strong>in</strong> tubular objects the statistics<br />

was not very mean<strong>in</strong>gful, because only a few tube elements were detectable (about 90%<br />

undetected) due to low contrast, noise, and low resolution. For all successfully identified<br />

vessels, the absolute radius error stayed with<strong>in</strong> an one voxel range (<strong>in</strong>ter-slice resolution).<br />

Note that the used graph cut segmentation is only able to produce voxel accurate segmentations.<br />

We also scored the segmentation accuracy on liver CT datasets <strong>in</strong> terms <strong>of</strong><br />

cl<strong>in</strong>ical usability for surgical plann<strong>in</strong>g (Section 5.3.2). The majority <strong>of</strong> segmented branches<br />

were scored as ”good“ and no branch was scored as ”poor“, even for datasets with ”poor“<br />

data quality. For low quality datasets with only few visible generations, the segmentation<br />

tended to be scored as ”ok“ toward the distal parts <strong>of</strong> the vessel trees where the contrast<br />

almost vanishes.<br />

Robustness: Our method performed robustly on the cl<strong>in</strong>ical datasets <strong>of</strong> the liver CT<br />

data as shown <strong>in</strong> our evaluation. For example, it produced correct results <strong>in</strong> disturbed<br />

regions caused by adjacent tumors (Figs. 5.9 and 5.12). All liver datasets utilized <strong>in</strong> our<br />

evaluation conta<strong>in</strong>ed multiple overlapp<strong>in</strong>g vessel trees that had to be separated, and 11<br />

out <strong>of</strong> the 15 datasets had pathological variations where other methods are likely to fail,<br />

as discussed <strong>in</strong> Section 5.3.3.<br />

5.5 Conclusion<br />

In this chapter, we presented and validated an approach for the segmentation and separation<br />

<strong>of</strong> the livers blood vessel trees. In contrast to other approaches, our method<br />

performs an identification <strong>of</strong> tubular objects followed by a a structural analysis to obta<strong>in</strong><br />

the structure <strong>of</strong> the different vessel trees. This structure <strong>in</strong>formation is then utilized as

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