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Segmentation of 3D Tubular Tree Structures in Medical Images ...

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Chapter 8<br />

Conclusion and Outlook<br />

Contents<br />

8.1 Conclusion . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 125<br />

8.2 Directions for Future Work . . . . . . . . . . . . . . . . . . . . . 128<br />

8.1 Conclusion<br />

In this work we were deal<strong>in</strong>g with the segmentation <strong>of</strong> <strong>3D</strong> tubular tree structures <strong>in</strong> medical<br />

images. In the <strong>in</strong>troduction, we outl<strong>in</strong>ed the general requirements and objectives<br />

for different applications <strong>in</strong> this field, emphasiz<strong>in</strong>g the importance <strong>of</strong> the structural correctness,<br />

and reviewed related work on vessel/airway segmentation. Based on that we<br />

presented a general approach for segmentation <strong>of</strong> branched tubular networks (Section 1.2)<br />

that puts a strong focus on the structural correctness <strong>of</strong> the segmentation results. The<br />

approach consists <strong>of</strong> a tube extraction step, a group<strong>in</strong>g and l<strong>in</strong>kage step, and the actual<br />

tube segmentation step.<br />

We developed and <strong>in</strong>vestigated methods for each <strong>of</strong> these process<strong>in</strong>g steps, lead<strong>in</strong>g<br />

to a set <strong>of</strong> flexible methods that can be utilized <strong>in</strong> various applications. In particular,<br />

<strong>in</strong> Chapter 2 we developed a novel approach for detection <strong>of</strong> tubular objects based on<br />

the GVF that addresses limitations <strong>of</strong> these typically used Gaussian scale space based<br />

methods and compared it to promis<strong>in</strong>g TDFs known from the literature. In Chapter 3<br />

we proposed two methods for group<strong>in</strong>g and l<strong>in</strong>kage <strong>of</strong> unconnected tubular structures<br />

<strong>in</strong>to tubular tree structures, one enabl<strong>in</strong>g an extraction <strong>of</strong> high quality centerl<strong>in</strong>es <strong>in</strong> that<br />

deviate significantly from the typical tube shape, while the other one allows for a separation<br />

<strong>of</strong> <strong>in</strong>terwoven tubular tree structures as well as handl<strong>in</strong>g <strong>of</strong> various k<strong>in</strong>ds <strong>of</strong> disturbances.<br />

125

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