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Segmentation of 3D Tubular Tree Structures in Medical Images ...

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Chapter 3<br />

Group<strong>in</strong>g and L<strong>in</strong>kage <strong>in</strong>to<br />

Connected Networks<br />

Contents<br />

3.1 Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 47<br />

3.2 Structure Based Approach . . . . . . . . . . . . . . . . . . . . . . 49<br />

3.3 Image Based Approach . . . . . . . . . . . . . . . . . . . . . . . . 51<br />

3.4 Experiments . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 54<br />

3.5 Dicussion and Conclusion . . . . . . . . . . . . . . . . . . . . . . 63<br />

3.1 Introduction<br />

In the last chapter we presented different methods for the identification and extraction<br />

<strong>of</strong> tubular objects from medical images. With these methods major parts <strong>of</strong> tubular tree<br />

structures can be already described. However, the methods are not capable <strong>of</strong> cop<strong>in</strong>g<br />

with branch<strong>in</strong>g areas or other areas where the appearance <strong>of</strong> the vessels/airways strongly<br />

deviates from the typical tube shape. This may be because <strong>of</strong> stenosis, aneurysms, or<br />

tumors where the shape <strong>of</strong> the vessels/airways is perturbed, or <strong>in</strong> case <strong>of</strong> imag<strong>in</strong>g artifacts<br />

or adjacent structures with<strong>in</strong> the same gray value range. Due to these cases the<br />

tubular structures extracted with methods as the ones presented <strong>in</strong> the last chapter are<br />

unconnected. A second issue not addressed with TDFs is that they identify all tubular<br />

structures <strong>in</strong> a given volume <strong>of</strong> <strong>in</strong>terest and they do not dist<strong>in</strong>guish between multiple<br />

potentially <strong>in</strong>terwoven tubular tree structures. Consequently, such structures need to be<br />

separated <strong>in</strong> an additional process<strong>in</strong>g step.<br />

47

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