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158 Fighting the Diseases of Poverty<br />

As such, these general institutional failures greatly reduce the<br />

incentives to develop new medicines, especially for diseases that<br />

primarily affect the poor. In addition, there are several specific issues<br />

in the institutions of many poorer countries that negatively affect<br />

incentives to develop new medicines.<br />

Weak intellectual property legislation in low and middleincome<br />

countries<br />

Some have claimed that patents create a barrier to access to medicines<br />

by increasing prices. While this is theoretically plausible, this<br />

scenario still does not explain the low rate of access to medicines<br />

that are already off patent and thus open to competitive, genericbased<br />

production.<br />

It is true that when a state grants a patent, it provides the<br />

inventor with temporary exclusivity over the patent product or<br />

process. This can incur real costs, including the possibility to keep<br />

prices artificially high when, in absence of legal protection, market<br />

forces would drive prices down to their marginal cost – the lowest<br />

price at which a good can be sold without the producer making a<br />

loss. However, as Amir Attaran has shown, more than 98 per cent of<br />

drugs on the WHO’s ‘Essential Medicines’ list are not patented in<br />

any poor country. As we have also illustrated, there are many factors<br />

that conspire against access, but patents on these specific medicines<br />

are not one of them (Attaran, 2004). In any case, these criticisms of<br />

patent protection must also be weighed against their benefits.<br />

When it comes to creating incentives to encourage the development<br />

of new medicines for the diseases of poverty, protection of<br />

intellectual property (IP) can play a crucially important role. The<br />

high cost of developing a new pharmaceutical product (estimated at<br />

upwards of $500 million in the US) (DiMasi et al., 2003), combined<br />

with the relatively low cost of copying the same product (typically<br />

a few millions of dollars), means that developers must be assured<br />

that they ‘own’ the product before they will commit such substantial<br />

sums.<br />

Patents stimulate competition in several important ways that

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