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Yablokov: Nonmalignant Diseases after Chernobyl 125fully answered. It is clear that continued detailedobservations are needed to document thespread and virulence <strong>of</strong> infectious and parasiticdiseases among people in all <strong>of</strong> the contaminatedterritories.5.12. Congenital MalformationsThere are several thousand large and smallcongenital malformations or anomalies. Onetype has a strong genetic background (see Section5.3 above for details) and the secondtype includes developmental anomalies resultingfrom impacts during embryonal development.Among them are the so-called “large”congenital malformations (CMs), which are<strong>of</strong>ten the only ones <strong>of</strong>ficially registered asanomalies. The other developmental anomaliesarise as a result <strong>of</strong> damage during prenataldevelopment and can be genetic, caused by mutations,or teratogenic, caused by toxic externalinfluences, usually occurring up to the first 16weeks <strong>of</strong> pregnancy.Wherever there was Chernobyl radioactivecontamination, there was an increase in thenumber <strong>of</strong> children with hereditary anomaliesand congenital malformations. These includedpreviously rare multiple structural impairments<strong>of</strong> the limbs, head, and body (Tsaregorodtsev,1996; Tsymlyakova and Lavrent’eva, 1996;Goncharova, 2000; H<strong>of</strong>fmann, 2001;Ibragymova, 2003; and others).This section presents data concerningcongenital malformations and developmentalanomalies.5.12.1. Belarus1. The frequency <strong>of</strong> the occurrence <strong>of</strong> CMs,which was stable up to 1986, increased noticeablyafter the catastrophe. Although theincrease in CMs is marked mainly in theheavily contaminated territories, significant increasesin CM morbidity were registered forthe whole country, including the less contaminatedVitebsk Province (Nykolaev and Khmel’,1998).TABLE 5.67. Incidence (per 1,000 Births) <strong>of</strong> theOfficially Accounted for Congenital Malformationsin Belarussian Districts with Different Levels <strong>of</strong>Contamination, 1982–1992 (Lazjuk et al., 1996a;Goncharova, 1997)Level <strong>of</strong> contaminationYear 1–5 Ci/km 2 >15 Ci/km 2

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