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Yablokov: Nonmalignant Diseases after Chernobyl 69TABLE 5.10. Number of Mutant Cells and Incidence of Chromosomal Aberrations (per 100Metaphases) among Women with Uterine Myoma in the Contaminated Territories of Tula and BryanskProvinces (Tsyb et al., 2006)Metaphases, Mutant cells, Aberrations, Contamination,n n n Bq/m 2Novozybkovsky District (n = 22) No data 6.2 ± 0.3 ∗ No data 708Klintsovsky District (n = 97) 18,703 5.3 ± 0.5 ∗ 4.27 ± 0.3 ∗ 322Uzlovaya Station (n = 100) 19,600 4.6 ± 0.3 2.30 ± 0.1 171Obninsk (n = 42) 12,779 4.0 ± 0.2 2.12 ± 0.1 Control∗ Differences from the control are significant.11. The number of lymphocytes with mutationsof T-locus (TCR) and the number of chromosomalaberrations correlated with a level ofradiation contamination in women with uterinetumors (myomas) who continued to live in theheavily contaminated Novozybkov and Klintsydistricts, Bryansk Province, and in UzlovayaStation, Tula Province (Table 5.10).12. The number of chromosomal aberrationsamong inhabitants of the contaminatedterritories in Bryansk Province is higher thanamong people living in less contaminated areas(Table 5.11).13. Inhabitants of the heavily contaminatedKlintsy and Vyshkov districts of BryanskProvince demonstrate a significantly highermitotic index in comparison with controls(Pelevina et al., 1996).14. Among 248 individuals aged 15 to 28years surveyed, the incidence of dicentrics andcentric rings is two- to fourfold higher thanamong control groups. Among those radiatedin utero, the frequency of occurrence of suchaberrations is fivefold higher than in controls(Sevan’kaev et al., 2006).15. Among inhabitants of four contaminateddistricts of Oryol Province, the incidenceof gene mutations on locus T-cellular receptor(TCR) and on locus glycophorin (GPA) ishigher than in controls (Sevan’kaev et al., 2006).16. Among 336 surveyed fertile womenfrom the contaminated Uzlovaya Station,Tula Province, and Klintsy District, BryanskProvince, the incidence of chromosomal exchangeaberrations was 0.13 ± 0.03 and 0.37 ±0.07 compared to controls, which was two- tosixfold less (0.6 ± 0.04; Ivanova et al., 2006).17. The number of lymphocytic and marrowchromosomal mutations correlated withthe radiation dose among liquidators and inhabitantsof Pripyat City within 3 months afterthe catastrophe and were manifestly higherthan among controls (Table 5.12) (Shevchenkoet al., 1995; Svirnovsky et al., 1998; Bezhenar’,1999; Shykalov et al., 2002; and others).18. The number of nonstable (dicentrics,acentric fragments, and centric rings) and stableaberrations (translocations and insertions)in liquidators was significantly higher in thefirst year after the catastrophe (Shevchenkoet al., 1995; Shevchenko and Snegyreva, 1996;Slozina and Neronova, 2002; Oganesyan et al.,2002; Deomyna et al., 2002; Maznik, 2003; andothers; Figure 5.1).TABLE 5.11. Incidence of Chromosomal Aberrations among Inhabitants of the Contaminated Territoriesof Bryansk Province (Snegyreva and Shevchenko, 2006)Individuals, n Cells, n Aberrations, n Including dicentricsBryansk Province 80 21,027 1.43 + 0.08 ∗ 0.10 + 0.02 ∗Control 114 51,430 0.66 ± 0.04 0.02 ± 0.01∗ Differences from control are significant.