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LTQ Orbitrap XL Hardware Manual

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type and selected ion monitoring (SIM) scan<br />

type.<br />

MSDS Material Safety Data Sheet<br />

MS/MS Mass spectrometry/mass spectrometry, or<br />

tandem mass spectrometry is an analytical<br />

technique that involves two stages of mass<br />

analysis. In the first stage, ions formed in the ion<br />

source are analyzed by an initial analyzer. In the<br />

second stage, the mass-selected ions are<br />

fragmented and the resultant ionic fragments are<br />

mass analyzed.<br />

MSn scan mode The scan power equal to 1 to 10,<br />

where the scan power is the power n in the<br />

expression MSn. MSn is the most general<br />

expression for the scan mode, which can include<br />

the following:<br />

• The scan mode corresponding to the one stage<br />

of mass analysis in a single-stage full-scan<br />

experiment or a selected ion monitoring (SIM)<br />

experiment<br />

• The scan mode corresponding to the two stages<br />

of mass analysis in a two-stage full-scan<br />

experiment or a selected reaction monitoring<br />

(SRM) experiment<br />

• The scan mode corresponding to the three to<br />

ten stages of mass analysis (n = 3 to n = 10) in a<br />

multi-stage full-scan experiment or a<br />

consecutive reaction monitoring (CRM)<br />

experiment.<br />

See also MS scan modes and MS/MS.<br />

multipole A symmetrical, parallel array of<br />

(usually) four, six, or eight cylindrical rods that<br />

acts as an ion transmission device. An RF voltage<br />

and dc offset voltage are applied to the rods to<br />

create an electrostatic field that efficiently<br />

transmits ions along the axis of the multipole<br />

rods.<br />

m/z Mass-to-charge ratio. An abbreviation used to<br />

denote the quantity formed by dividing the mass<br />

of an ion (in u) by the number of charges carried<br />

Glossary: MSDS<br />

by the ion.<br />

For example, for the ion C 7 H 7 2+ , m/z = 45.5.<br />

n nano (10 -9 )<br />

nanospray ionization (NSI) A type of<br />

electrospray ionization (ESI) that accommodates<br />

very low flow rates of sample and solvent on the<br />

order of 1 to 20 nL/min (for static nanospray) or<br />

100 to 1000 nL/min (for dynamic nanospray).<br />

NCBI National Center for Biotechnology<br />

Information (USA)<br />

NIST National Institute of Standards and<br />

Technology (USA)<br />

NMR Normal Mass Range<br />

NSI See nanospray ionization (NSI).<br />

octapole An octagonal array of cylindrical rods<br />

that acts as an ion transmission device. An RF<br />

voltage and dc offset voltage applied to the rods<br />

create an electrostatic field that transmits the ions<br />

along the axis of the octapole rods.<br />

OD outside diameter<br />

OT <strong>Orbitrap</strong><br />

Ω ohm<br />

p pico (10 -12 )<br />

Pa pascal<br />

PCB printed circuit board<br />

PDA detector Photodiode Array detector is a<br />

linear array of discrete photodiodes on an<br />

integrated circuit chip. It is placed at the image<br />

plane of a spectrometer to allow a range of<br />

wavelengths to be detected simultaneously.<br />

PE protective earth<br />

PID proportional / integral / differential<br />

Thermo Fisher Scientific <strong>LTQ</strong> <strong>Orbitrap</strong> <strong>XL</strong> <strong>Hardware</strong> <strong>Manual</strong> G-5

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