12.07.2015 Views

Food Security - National Agricultural Biotechnology Council ...

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June Medford, a professor of biology at Colorado State University,is a leader in the field of plant synthetic biology. Shereceived her BS in botany from the University of Maryland anda PhD in biology from Yale, followed by postdoctoral trainingwith the Plant Molecular Biology group at Monsanto.Dr. Medford’s research focus is on plant synthetic biology, the forward engineeringof plants for specific purposes, both basic and applied. She has developed asynthetic signal-transduction system based on conserved histidine kinase componentsand a field-level synthetic readout system. By linking these syntheticsystems together with computationally re-designed receptors, the Medford labhas produced the first sentinels to allow plants to serve as inexpensive and highlyspecific detectors of substances such as explosives, environmental pollutantsand chemical agents. Detection levels are approximately 10- to 100-fold betterthan the detection abilities of dogs. Work is in progress to add ultra-sensitivityand memory for specific application (e.g. transportation hubs) and expand thedetection platform to biological agents. Furthermore, the synthetic system is abiological input-output system and, hence, is being used to control biofuel andagronomic traits.86 <strong>Food</strong> <strong>Security</strong>: The Intersection of Sustainability, Safety and Defense

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