Methods in Anopheles Research - MR4

Chapter 2 : Anopheles Biology Laboratory and Culture2.6 Basic Anopheles Population GeneticsPage 5 of 6Alleles can have a positive or negative fitness depending on the environment.Fitness can be expressed as an adjustment variable ‘s’ to the allele frequency. For example, a neutralallele with no effect on fitness has a relative fitness of ‘ s = 0 ’ such that the allelic frequency adjustmentwould be q ( 1- s ) or q (1 - 0 ) or simply q. On the other hand, a lethal has a fitness of 1 so that q ( 1- s )or q (1 - 1 ) becomes simply 0 (zero).Alleles with fitness of