Chapter-1 / Physiological Foundations - WHNLive Public Library

Table 2 The quality of the 02 status is approximately equal to energetic state02 transport into body tissue 02 consumption in body tissue:00 2 [I 02/min ] = 11 x COP[llminl x Hb[021The meanings:Basic mechanisms and functions 19=Utilization (degree of exploitation) of the 02 binding capacity of the blood measured at restA relative characteristic value, usually applicable for diagnostic purposes, as the resting COP usuallyonly changes slowly with age and fitness, determined by means of the 02 binding curve of theblood, using measurements of the arterial and venous resting P02'COP =Cardiac output (at rest) =stroke volume SV x pulse frequency f.Determined, e.g. by spirometric methods, reduced with age, but regenerable to some extent by02MT + exercise.Hb= Haemoglobin content of the blood. In the individual roughly constant ~ 160 g Hb/I (1 g Hb binds1.34 ml O2) ~ 0.2144 I 02/1 blood.A60Measurements of thedoily 2+-h cycle 50of the 02 -saturationdifference Vin theblood in aheallhymole (39 years)frea ted with O 2 Hr.The deYiafions of'lare largely cond/1ionedby alterations in the '1venous resting pOz 20and are roughlyproportional to thedeyiations of 0/ up/oke10/1st maximum....tirednessIfalling asleep.~-I2nd maximum/1\J ,1\VJ 1\ /i'v ~~ I \Vnoclurno minimumap~rox. 3hrs afterfa li~asleep (phose of- poss 't nocturnalcnmJo 681012 141618 20 22 24I2I4 6hB30%20Representation of the 70doily 24-h cycleof the mean PhySiOIOgiCal1 0performance -70capacity L accordingto 0. Bra! [el 481. -20P stands for percent P-30of yoria/ion fromdoily mean.-50earN I measuremenf san f dar, d meosurement1sfmaximum ~lI "- I -2nd maximum/ f'.I-- ,"- ...V\\~J~ I\ I\ 1/-60681012 14 16time of day18 20 22 2426h. and two minima of the energetic status in the daily 24 hour cycle is clear-Fig. 10 The occurrence of t~o md~;;::nce '1"1 (A) and also in O. Graf's findings on the course of the mean physiol-Iy reflected in the 02 saturation I r " ,ogical performance capacity (B)