Chapter-1 / Physiological Foundations - WHNLive Public Library

logical foundations13IrPtz12.........- ....... ~ .,f-IJ960 8o 2 4 614 16 188 KJ 12It ..Fig.47 Example of the behavior of the arterial resting P02 during the 02MT treatment of real nonresponders(slowing of respiration by 02 excess). Mean values of 3 patients [92]lOllThe main indication for the 02MT proceduresshould be seen as the prevention of illness.These procedures should always be used forprophylaxis at certain time intervals derivedfrom P02 measurements, in cases of pathologicalmovement disability or after approximatelythe 55th year of life (even earlier in exceptionalcases of levels P0 2 _ art < 70 mmHg Q9.3 kPa). In youth and middle age daily strenousexercise training (leisure sport, jogging, runningetc.) [12, 88, 95] is generally sufficient as ameans of permanently increasing the value of fl,or the Po 2 - art .1.1.8.6 Lung-conditioned, 02MT partial nonresponden; influencing facton, contra-indicationsLike every other therapeutic procedure, the02MT also has contraindications and therapynonresponders. There is usually a contraindicationfor patients in whom the body's respiratoryregulation is not controlled as normal bythe PC02 of the blood, but primarily by thelow P0 2of the blood (Loeschke's effect [96,97]). In these patients the 02MT can only beperformed with special precautions·.In some patients, as Fig. 47 shows, even a reductionin the arterial resting P0 2 of roughly5 mmHg due to the 02MT procedure was observed.In these patients a drop in the P02- venunder 02MT must have been attained.As is known [96, 97], the arterial hypoxemiawhich exists in generalized respiratory insufficiencyis associated with an 02 deficient controlof ventilation. Application of O2 eliminates• Artificial respiration if necessary. Recognition ofparen with abnormal respiration regulation bymeans of initial test, e.g. with checking of the bloode. or the dangers of artificial respiration for patienwith severe chronic respiratory insufficiency02 air mixtures with 02 proportions> 50%(JellPUatory depre ion, arterial P 02 60 mmHg,the adequate stimulus for the 02 deficiencyreceptor, and so alveolar hypoventilation (withthe reduction in the resting P02-8rt alreadymentioned), and also, in such cases, in increasein the PC02_art (hypercapnia) and the risk ofapnea can occur. When the generalized respiratoryinsufficiency is considered to be a relativecontraindication [98, 99], which is absoluteunder outpatient conditions, and when attentionis carefully paid to the blood gas analysisand the acid-base balance in partial respiratoryinsufficiency, where we have never observedany dysfunctions, the 02MT has proven iprincipal applicability under these circumstances,too. The temporary inhalation of.oxygen in patients with chronic lung di aand consecutive cor pulmonale has been u­cessfully practised with the aim of redu ingresistance in the lesser circulation for[100]. Whether, and to what e tent, thcould have a comparable If ct i to bsubject of future inve tigation ppropriin pulmologically ori nt d tr atm nt nHowever, there can hardly b any ri f rpati nt in our th rapy progr m . hdoubling or trebling of th O 2 ont n iinhalation air in th 6 h pr do MT, or th t chnology d v 1 d f r ·