Chapter-1 / Physiological Foundations - WHNLive Public Library

-'0 y 101091cai oundatlons80%6050l~'lJ)20.. • • ••••..,t..- • •• • I., •• I·• •I-,-I_ -••p••••II. •t.-....I: •~ 0 ••0• ••• • • 0• • • • ••-'" • •,.0 ,..• -. -0~,..20 30 40 500.~ -0 000• •0 00 o~ .0 000 o __B0,--o off' c~ 0- -0 00o~ 0 o 0- 060CIfJt --....... -~ g ~oooo qp 0 070Fig. 19 Measurement of the utilizationfactor 11 of the oxygen binding capacityof the blood before (0) and after (.)02MT, dependent on age, in 88 patientsof the sanatorium Dr. med. S. H. Wolf,Bad Wildungen, FRGof patients, were achieved in another clinic. Anaverage (lasting) increase in the arteriovenoussaturation difference 11 from 100% beforetherapy to 239 % after treatment occurred inthe Bad Wildungen group of patients. In asmaller patient sample in Bad FUssing the increaseafter therapy was 230 %. It can thereforebe established that in patients in about thesame degree of need of therapy the same improvementsof the O2 status to about 230 %occur. In healthy volunteers and with the sameP02 levels as in Fig. 18, the mean increase dueto 02MT would be 133 %.The therapy effect in healthy individuals isthus, according to these measurements, onlyapproximately one quarter of the effect inweakened patients.It follows from this that in the testing of theeffect of the oxygen multistep therapy, thecomposition of the patients' sample plays adecisive role.1.1.5.4 Determining the resting O 2 uptake of the organism as an absolute characteristic value ofthe O 2 statusIn the framework of research and in specialcases in 02MT treatments, when cardiovascular·training is combined with the procedure andthen the resulting changes in the cardiac outputare to be documented, a codetermination of theO 2 uptake, at rest, of the organism almostbecomes a necessity.A series of methods, invasive and non-invasive,has been designed, e.g. [56, 57], for the directdetermination of the cardiac output (at physicalrest and under exertion). After previous experimentswith the impedance-cardiographic method,which proved not to be particularly suitedto the determination of absolute valu s of thecardiac output, the spirometric unit in Fig. 20was developed for direct measurement of theresting O 2 uptake. The arrangement also allowsthe determination of the maximal O 2 uptakeand CO 2 production of the organism. Theprinciple discussed below has the advantagethat, in inhalation, we are not dealing unphysiologicallywith pure oxygen, but with air ofnatural composition. The arrangement shownmakes possible the extremely accurate measurementof the O 2 uptake at rest and a surpri inglaccurate calculation of the absolute levels ofthe resting cardiac output with th help of thfollowing well-known equation re ulting fr mTable 2: