rologie i - European Congress of Virology

5 th European Congress of VirologyWORKSHOP 9: “ANTIVIRAL THERAPY AND RESISTANCE TO CHRONIC VIRAL INFECTION”Amphitheater (p. S86)Chairpersons: Henri AGUT (Paris, FRANCE) & Christine GINOCCHIO (Lake Success, USA)15h00 – 15h30 Keynote: Cell-cell transmission governs spread and immune escape of HIV-1Alexandra TRKOLA (Zurich, SWITZERLAND)15h30 – 15h45 Simultaneous Hepatitis C virus (HCV) NS3 protease and NS5B polymerase resistance testing by analternative error correction 454 deep sequencing pipeline, F. Xavier LÓPEZ LABRADOR (Valencia, SPAIN)15h45 – 16h00 Experience of HCV resistance after 2 years antiproteases clinical practice; detection ofresistance mutations after long period of undetectability, Christophe RAMIERE (Lyon, FRANCE)16h00 – 16h15 Mutagenesis of HIV 1 reverse transcriptase ribonuclease H domain defines residuescontributing to ribonuclease H activity inhibition by diketo acids, Angela CORONA (Cagliari, ITALY)16h15 – 16h30 New anti CMV drugs alone or in combination: efficacy in cell culture and placental explantsDeborah ANDOUARD (Limoges, FRANCE)16h30 – 16h45 Generation and Characterization of defined HCMV UL97 and UL54 mutations associatedwith drug resistance, Lena FISCHER (Tübingen, GERMANY)16h45 – 17h00 Herpes simplex virus infection control with novel small interfering RNA poolsHenrik PAAVILAINEN (Turku, FINLAND)17h00 – 17h15 Biophysical characterization and antiviral effects of non canonical DNA structuresin the herpes simplex virus type 1 Genome, Sara ARTUSI (Padova, ITALY)WORKSHOP 13: “VIRAL REPLICATION STRATEGIES” Room Gratte-Ciel 1, 2, 3 - Level 2 (p. S89)Chairpersons: Luis ENJUANES (Madrid, SPAIN), Juan ORTIN (Madrid, SPAIN)15h00 – 15h3015h30 – 15h4515h45 – 16h0016h00 – 16h1516h15 – 16h3016h30 – 16h4516h45 – 17h0017h00 – 17h15Keynote: Influenza polymerase host adaptation, Wendy Barclay (London, UNITED KINGDOM)Processive RNA synthesis, repair and capping activities embedded in a SARS Coronavirusmulti protein complex, Lorenzo SUBISSI (Marseille, France)Crystal structure of the N0 P complex of Nipah virus and of VSV provide new insights intothe encapsidation mechanism of the Paramyxoviridae and Rhabdoviridae, Filip YABUKARSKI(Grenoble, FRANCE)Role of host factors in enterovirus RNA replication, Frank VAN KUPPEVELD(Utrecht, THE NETHERLANDS)Phosphatidylinositol 4 kinase III beta enhances human rhinovirus replicationby recruiting the oxysterol binding protein to ER Golgi derived membranes,Pascal S ROULIN (Zurich, SWITZERLAND)A Structural Basis for the Oligomer Assembly and Host Chromatin Interactionof Two Gamma2 Herpesviral LANA Proteins and Their Role in Viral Persistence,Magdalena WEIDNER GLUNDE (Hannover, GERMANY)Unscheduled mitotic entry of HCMV infected cells leads to chromosomal damage and mitoticcell death, Martin EIFLER (Berlin, GERMANY)BET proteins as cofactors for gammaretroviral integration,Saumyashree GUPTA (Hannover, GERMANY)Virologie, Vol. 17, supplément 2, septembre 2013S29