Drug List Book

Zocor
(Simvastatin)
SIM-va-sta-tin
Classification: HMG-CoA
Reductase Inhibitor
IFU: Hyperlipidemia
Action: Inhibits hepatic enzyme
HMG-CoA reductase,
interrupting cholesterol
synthesis and low-density
lipoprotein (LDL) consumption
Dosage: 5 mg, 10 mg, 20 mg
Route: P.O.
Adverse Reaction: flatulence,
dyspepsia, constipation, eczema,
increased creatine
phosphokinase, dizziness,
fainting, fast or irregular
heartbeat, nausea, diarrhea,
abdominal pain
Interactions: Digoxin: Slightly
increased digoxin blood level
Page 197