Drug List Book
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Flovent HFA<br />
(Fluticasone)<br />
floo-TIK-a-zone<br />
Classification: Corticosteroid<br />
IFU: Allergic rhinitis<br />
Action: Synthetic<br />
glucocorticosteroid with<br />
potent anti-inflammatory<br />
activity. Inflammation is an<br />
important component in the<br />
pathogenesis of asthma.<br />
Glucocorticosteroids inhibit<br />
many cell types and mediator<br />
production or secretion<br />
involved in the asthmatic<br />
response. These<br />
anti-inflammatory actions of<br />
fluticasone may contribute to<br />
its efficacy in asthma.<br />
Dosage: 44 mcg, 50 mcg, 100 mcg,<br />
110 mcg, 220 mcg, 250 mcg, 500 mcg<br />
Route: Inhalation<br />
Adverse Reaction: headache,<br />
pharyngitis, oral candidiasis,<br />
upper respiratory tract<br />
infection<br />
Interactions: Ketoconazole:<br />
Increased mean fluticasone<br />
levels. Use care when giving<br />
fluticasone with long-term<br />
ketoconazole and other known<br />
cytochrome P-450 3A4 inhibitors<br />
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