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Drug List Book

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Evista<br />

(Raloxifene)<br />

ra-LOX-i-feen<br />

Classification: Selective<br />

estrogen receptor modulator<br />

IFU: Osteoporosis<br />

Action: Reduces resorption of<br />

bone and decreases overall bone<br />

turnover, These effects on bone<br />

are manifested as reductions in<br />

serum and urine levels of bone<br />

turnover markers and increases<br />

bone mineral density.<br />

Dosage: 60 mg<br />

Route: P.O.<br />

Adverse Reaction: sinusitis,<br />

infection, flu syndrome, hot<br />

flashes, depression, insomnia,<br />

chest pain, weight gain, fever<br />

Interactions: Cholestyramine:<br />

Causes significant reduction in<br />

absorption of raloxifene. Avoid<br />

concomitant use.<br />

Page 70

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