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Download the ESMO 2012 Abstract Book - Oxford Journals

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Annals of Oncology<br />

progression-free survival very useful from <strong>the</strong> viewpoint of side effects, even in phase<br />

III clinical trials.<br />

Disclosure: All authors have declared no conflicts of interest.<br />

1705 PROSPECTIVE EVALUATION OF THE EFFECT OF A MANUAL<br />

FOR DIABETIC PATIENTS WHO RECEIVE CANCER<br />

CHEMOTHERAPY<br />

H. Kato1 , T. Mineta2 , K. Chikamori2 , N. Hamajima2 , S. Koyama3 , H. Kushihara3 ,<br />

B. Hiroyuki4 , M. Yamauchi5 , K. Kawada1 and F. Nomura1 1<br />

Medical Oncology, Japanese Red Cross Nagoya First Hospital, Nagoya,<br />

JAPAN, 2 Nursing, Japanese Red Cross Nagoya First Hospital, Nagoya, JAPAN,<br />

3<br />

Pharmacy, Japanese Red Cross Nagoya First Hospital, Nagoya, JAPAN,<br />

4<br />

Nutrition, Japanese Red Cross Nagoya First Hospital, Nagoya, JAPAN,<br />

5<br />

Endocrinology and Diabetes, Japanese Red Cross Nagoya First Hospital,<br />

Nagoya, JAPAN<br />

Background: How to safely administer cancer chemo<strong>the</strong>rapy to patients with<br />

diabetes mellitus is an important issue. Our institution is a general core hospital in<br />

Japan. In 2010, we surveyed <strong>the</strong> current status of diabetic patients given cancer<br />

chemo<strong>the</strong>rapy. Adequate medical examinations were not performed. In 2011, we<br />

designed a manual for diabetic patients who receive cancer chemo<strong>the</strong>rapy. We now<br />

report an improvement in medical examinations of diabetic patients who receive<br />

cancer chemo<strong>the</strong>rapy since introducing our manual.<br />

Methods: We decided that adequate medical examinations should include <strong>the</strong><br />

following: adequate measurement of blood sugar levels; evaluation of <strong>the</strong> patient by a<br />

diabetologist; making standards for decreasing <strong>the</strong> dose of steroids given before<br />

cancer chemo<strong>the</strong>rapy; and making standards for nutritional guidance. We compared<br />

<strong>the</strong> present status (as of March <strong>2012</strong>) with that before <strong>the</strong> introducing our manual<br />

for diabetic patients receiving cancer chemo<strong>the</strong>rapy.<br />

Results: The proportion of diabetic patients increased from 12% to 19%. The<br />

rate of measuring blood sugar levels at <strong>the</strong> start of new regimens of<br />

chemo<strong>the</strong>rapy increased from 69% to 72%. The rate of adequate continuous<br />

monitoring of blood sugar levels increased from 48% to 81%. The rate of<br />

evaluation by a diabetologist increased from 36% to 50%. The rate of decreased<br />

premedication with steroids increased from 55% to 66%. The rate of providing<br />

nutritional guidance was unchanged (23% to 24%).<br />

Conclusions: The rates of adequate continuous monitoring of blood sugar levels,<br />

decreasing premedication with steroids, and evaluation by a diabetologist improved.<br />

The increase in <strong>the</strong> proportion of diabetic patients was attributed to adequate blood<br />

sugar examinations. However, <strong>the</strong> low rate of providing of nutritional guidance<br />

remains an unsolved problem.<br />

Disclosure: All authors have declared no conflicts of interest.<br />

Volume 23 | Supplement 9 | September <strong>2012</strong> doi:10.1093/annonc/mds416 | ix527

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