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McKay, Donald. "Front matter" Multimedia Environmental Models ...

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Whereas simple lethality experiments can be designed using air, water, or food as<br />

vehicles for chemical exposure, it is not always clear how concentrations in the solid<br />

matrices of soils and sediments relate to exposure or intake of chemical by organisms.<br />

It is difficult to design meaningful bioassays involving interactions between organisms,<br />

soils, and sediments. One approach is to decree that whatever target fugacity<br />

is developed for water be applied to sediment. This effectively links the target<br />

concentrations by equilibrium partition coefficients.<br />

A second method is to use concentrations to estimate exposure or dosage in units<br />

such as mg/day of chemical to an organism, which for selfish reasons is usually a<br />

human. Individual and total dosages can be estimated to reveal the more important<br />

routes. This calculation of dose is enlightening, because it reveals which medium<br />

or route of exposure is of most importance. Presumably, steps can then be taken to<br />

reduce this route by, for example, restricting fish consumption.<br />

Table 8.5 lists representative exposure quantities for several human age classes.<br />

Table 8.5 Representative Exposure Rates for Four Human Age Classes Derived<br />

Principally from the EPA Exposure Factors Handbook<br />

Age Classes<br />

Route

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