68° Congresso Nazionale SCIVAC: Le domande più frequenti in ...

68° CONGRESSO NAZIONALE SCIVAC 11-13 Marzo 2011 - Milano
LE DOMANDE PIÙ FREQUENTI IN RIPRODUZIONE CANINA E FELINA
Tutto quello che i vostri clienti osano spesso chiedere e a cui voi non sapete rispondere
14 th EVSSAR Congress - Advances in Feline Reproduction - March 11 th 2011
mg/kg of oestradiol benzoate, 3, 5 and 7 days after mismating. The efficacy
is around 95% (Sutton et al. 1997).
A more recent publication recommends one single injection of 0.2 mg/kg
2 days after mating (Tsutsui et al. 2006). According to these authors, the efficacy
seems unchanged.
Side effects: the best know secondary effect concerns the risk of induced
CEH-pyometra. According to most authors, pyometra after a pregnancy termination
treatment using oestrogens may develop in 7.3 to 15% of the cases
(Sutton et al. 1997, Eilts 2002).
Only aglepristone may be a safe and effective drug to medically terminate
pregnancy at this early stage.
We strongly recommend veterinarians first to perform a vaginal smear: it
allows veterinarians to know if the bitch is still in oestrus or if the bitch has
reached the dioestrus stage.
A recent meeting of specialists (Lennoz 2006) recommended veterinarians
waiting until the beginning of dioestrus to begin an abortive medical protocol
with antiprogestins.
This is due to the average 6 days residence time of aglepristone in the body
after subcutaneous administration. If a bitch is mated a little bit before
ovulation, when the progesterone plasma level is still low, and if she is treated
at once with aglepristone - which acts in under one week - it cannot be excluded
that she may still become pregnant, due to the long survival of sperm
in the genital tract.
2.2.2. The bitch is brought to consultation in early
pregnancy (before day 15 to 21 after mating, when a
pregnancy diagnosis is still impossible to make)
The advisability of medical treatment to terminate pregnancy at an early
stage is always open to discussion. Several studies have shown that many bitches
brought to veterinary consultation at this early stage are in fact not pregnant.
From our personal point of view, due to the relatively lower efficacy of
pregnancy termination at mid-term pregnancy (see paragraph 3.3), due to
ethical aspects (no live fetuses are visualized by bitch owners) and due the potential
development of side effects when an abortion is induced later in pregnancy,
we would rather recommend an early pregnancy termination when
owners can afford it financially.
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