APPENDICES. A systematic review and economic model of the ...

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Appendix 12
Core symptoms Educational performance Quality of life Adverse events
The proportion of participants reporting appetite loss
differed significantly between Arms 1 and 2, p = 0.001,
and between Arms 1 and 3, p = 0.13, but not between
Arms 2 and 3
Natural setting: Abbreviated Conners’ Scale
(teacher): mean (SD)
Arm 1: 16.40 (7.74); Arm 2: 7.94 (5.83); Arm
3: 7.82 (5.92)
Significant differences between Arms 1 and 2,
and between Arms 1 and 3 (p < 0.001)
Natural setting: Abbreviated Conners’ Scale
(parent): mean (SD)
Arm 1: 19.91 (6.02); Arm 2: 11.41 (6.23);
Arm 3: 9.49 (6.50)
Significant differences between Arms 1 and 2
(p < 0.001), Arms 1 and 3 (p < 0.001), Arms
2 and 3 (p < 0.05)
Laboratory setting: Abbreviated Conners’
Scale (teacher): mean (SD)
Arm 1: 7.03 (7.07); Arm 2: 4.03 (6.31); Arm
3: 3.75 (6.66)
Significant differences between Arms 1 and 2,
and between Arms 1 and 3 (p < 0.001)
Laboratory setting: Abbreviated Conners’
Scale (counsellor): mean (SD)
Arm 1: 12.70 (7.15); Arm 2: 9.91 (6.15); Arm
3: 9.26 (5.73)
Significant differences between Arms 1 and 2
and between Arms 1 and 3 (p < 0.001)
SKAMP Teacher ratings: graphical presentation
only
Conclusions Authors’ conclusions: This investigation supports the efficacy of Concerta long-acting formulation of MPH for parents who desire to
have medication benefits for their child throughout the day and early evening
Reviewer’s comments: No comments noted