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APPENDICES. A systematic review and economic model of the ...

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Study Intervention Participants Outcomes<br />

Additional outcomes<br />

Services Use by Children <strong>and</strong><br />

Adolescents–Parent Interview: use<br />

<strong>and</strong> dose <strong>of</strong> medication, use <strong>of</strong><br />

specialty mental health services, use<br />

<strong>of</strong> special education services<br />

Total withdrawals = 20 (at 14 months)<br />

Arm 1 = 8<br />

Arm 2 = 3<br />

Arm 3 = 3<br />

Arm 4 = 6<br />

Total withdrawals = 39 (93%) (24 months)<br />

Age<br />

8.5 years (mean); 0.8 years (SD)<br />

Arm 3<br />

Medication management plus<br />

Behavioural treatment<br />

Integration <strong>of</strong> all treatment<br />

components in Arms 1 <strong>and</strong> 2 (except<br />

biblio<strong>the</strong>rapy), such that information<br />

is shared amongst all involved in<br />

decision-making<br />

(Administered by<br />

<strong>the</strong>rapist–consultant, counselloraides)<br />

IQ<br />

100.9 (mean)<br />

Co-morbid disorders<br />

Anxiety disorder: n = 194 (33.5%)<br />

CD: n = 83 (14.3%)<br />

ODD: n = 231 (39.9%)<br />

Affective disorder: n = 22 (3.8%)<br />

Tic disorder: Total: n = 63 (10.9%)<br />

Mania/hypomania: n = 13 (2.2%)<br />

O<strong>the</strong>r co-morbid conditions (e.g. bulimia, enuresis): n = 1 (0.2%)<br />

Arm 4<br />

St<strong>and</strong>ard community care<br />

List <strong>of</strong> community mental health<br />

resources given to those without<br />

treatment provider; o<strong>the</strong>rwise<br />

referred back for treatment<br />

(Individuals administering medication<br />

not reported)<br />

© Queen’s Printer <strong>and</strong> Controller <strong>of</strong> HMSO 2006. All rights reserved.<br />

Diagnostic subtypes<br />

All children met criteria for ADHD Combined Type<br />

Health Technology Assessment 2006; Vol. 10: No. 23<br />

Additional information<br />

Previous medication:<br />

Total: n = 178 (31%): Arm 1: n = 46 (32%), Arm 2: n = 38 (26%),<br />

Arm 3: n = 44 (30%), Arm 4: n = 50 (34%)<br />

No significant differences were found across sites (p = 0.0001).<br />

Participants in <strong>the</strong> trial were not to have been in receipt <strong>of</strong> any<br />

neuroleptic medication in previous 6 months<br />

363

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