APPENDICES. A systematic review and economic model of the ...
APPENDICES. A systematic review and economic model of the ...
APPENDICES. A systematic review and economic model of the ...
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Study Intervention Participants Outcomes<br />
Core symptoms<br />
CBCL parent rated<br />
Teacher report form<br />
Inclusion criteria<br />
Diagnosis <strong>of</strong> ADHD<br />
Reference<br />
Tervo et al., 2002 93<br />
Co-existent problems<br />
Not reported<br />
Diagnostic criteria<br />
DSM-IV<br />
Arm 1<br />
Placebo<br />
Twice daily for 6 days<br />
(Individual administering medication<br />
not reported)<br />
Source<br />
Updated search<br />
Educational performance<br />
Not reported<br />
Number<br />
Total r<strong>and</strong>omised = 41 (male/female split not reported)<br />
Total withdrawals unclear<br />
Arm 2<br />
MPH<br />
0.05 mg/kg twice daily for 6 days<br />
(Individual administering medication<br />
not reported)<br />
Setting<br />
USA<br />
Psychological function<br />
Not reported<br />
The authors described withdrawals, but did not present <strong>the</strong>m separately<br />
for children with <strong>and</strong> without ADHD-MD<br />
Design<br />
Crossover trial<br />
Depression or anxiety<br />
Not reported<br />
Age<br />
10 years (mean); 2.86 years (SD)<br />
Quality <strong>of</strong> life<br />
Not reported<br />
Arm 3<br />
MPH<br />
0.3 mg/kg twice daily for 6 days<br />
(Individual administering medication<br />
not reported)<br />
Duration<br />
Total treatment period:<br />
3 weeks (6 days per<br />
treatment arm followed<br />
by a 1-day washout<br />
period)<br />
Adverse events<br />
Not reported<br />
IQ<br />
Not reported<br />
Co-morbid disorders<br />
Children with ADHD-MD were also included in <strong>the</strong> <strong>review</strong>, but data are<br />
not extracted here<br />
Additional outcomes<br />
Not reported<br />
Diagnostic subtypes<br />
Not reported<br />
© Queen’s Printer <strong>and</strong> Controller <strong>of</strong> HMSO 2006. All rights reserved.<br />
Additional information<br />
No relevant information reported<br />
Purpose<br />
To evaluate <strong>the</strong><br />
medication<br />
responsiveness <strong>of</strong><br />
children with ADHD<br />
(with or without motor<br />
dysfunction). Only data<br />
for children without<br />
motor dysfunction<br />
(ADHD-MD) have been<br />
extracted<br />
Health Technology Assessment 2006; Vol. 10: No. 23<br />
351