APPENDICES. A systematic review and economic model of the ...
APPENDICES. A systematic review and economic model of the ...
APPENDICES. A systematic review and economic model of the ...
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208<br />
Appendix 12<br />
Core symptoms Educational performance Quality <strong>of</strong> life Adverse events<br />
Not reported Problem Behaviour Checklist<br />
(parents): side-effects (Mean, SD)<br />
(1 = not at all; 4 = very much)<br />
Scores for:<br />
poor appetite/awake at<br />
night/headaches/<br />
‘tummyaches’/’side-effects <strong>of</strong><br />
drugs’<br />
Before drug:<br />
1.48 (0.87)/1.79 (1.01) /1.79<br />
(0.73) /1.93 (1.80)/1.34 (0.81)<br />
MPH:<br />
1.83 (0.97)/1.76 (0.91) /1.52<br />
(0.51) /1.62 (0.62)/1.59 (0.78)<br />
DEX:<br />
1.93 (1.03)/1.86 (0.92) /1.52<br />
(0.78) /1.52 (0.57)/1.59 (0.87)<br />
Poor appetite: placebo > MPH,<br />
p < 0.05; placebo > DEX,<br />
p < 0.01<br />
‘Tummyaches’: DEX > placebo,<br />
p < 0.05<br />
Davids’ Hyperkinetic Rating Scale<br />
(parents): poor schoolwork<br />
Before drug: 4.62 (1.29)<br />
MPH: 3.69 (1.28)<br />
DEX: 3.79 (1.18)<br />
Significance <strong>of</strong> difference not<br />
reported<br />
Problem Behaviour Checklist (parents): total score (mean, SD)<br />
Before drug: 190.07 (37.91)<br />
MPH: 152.28 (34.79)<br />
DEX: 146.97 (36.63)<br />
MPH = DEX, not significant<br />
Davids’ Hyperkinetic Rating Scale<br />
(teachers): poor schoolwork<br />
Before drug: 4.62 (1.29)<br />
MPH: 3.83 (1.28)<br />
DEX: 3.93 (1.33)<br />
MPH = DEX, not significant<br />
Problem Behaviour Checklist (parents): hyperactivity<br />
Before drug: 24.31 (4.66)<br />
MPH: 18.21 (5.61)<br />
DEX: 17.21 (5.45)<br />
Significance <strong>of</strong> difference not reported<br />
Problem Behaviour Checklist (parents): inattentive unproductiveness<br />
Before drug: 15.83 (4.32)<br />
MPH: 11.83 (3.79)<br />
DEX: 11.38 (3.39)<br />
Significance <strong>of</strong> difference not reported<br />
Conners’ Teachers’ Behaviour Problem Checklist: total score<br />
Before drug: 91.52 (16.70)<br />
MPH: 73.55 (22.35)<br />
DEX: 70.26 (18.33)<br />
MPH = DEX, not significant<br />
Conners’ Teachers’ Behaviour Problem Checklist: hyperactivity<br />
Before drug: 23.10 (4.50)<br />
MPH: 16.83 (5.50)<br />
DEX: 16.17 (4.64)<br />
Significance <strong>of</strong> difference not reported<br />
Conners’ Teachers’ Behaviour Problem Checklist: day-dreaming <strong>and</strong><br />
inattention<br />
Before drug: 14.97 (3.27)<br />
MPH: 12.10 (3.53)<br />
DEX: 12.03 (3.94)<br />
Significance <strong>of</strong> difference not reported<br />
Davids’ Hyperkinetic Rating Scale (parents): total score<br />
Before drug: 30.76 (3.40)<br />
MPH: 25.41 (5.19)<br />
DEX: 25.31 (5.57)<br />
MPH = DEX, not significant<br />
continued
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