APPENDICES. A systematic review and economic model of the ...
APPENDICES. A systematic review and economic model of the ...
APPENDICES. A systematic review and economic model of the ...
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362<br />
Appendix 12<br />
Study Intervention Participants Outcomes<br />
Core symptoms<br />
SNAP scale: inattention, hyperactivity<br />
<strong>and</strong> impulsivity subscales (parents,<br />
teachers)<br />
Abik<strong>of</strong>f Classroom Observational<br />
System: school-based core symptoms<br />
Inclusion criteria<br />
Inclusion criteria:<br />
1. 7–9.9 years old<br />
2. In grades 1–4<br />
3. In residence with same primary caretaker(s) for last 6 months or<br />
longer<br />
4. Score above 90th percentile on st<strong>and</strong>ardised teacher rating scales<br />
Reference<br />
MTA Cooperative<br />
Group, 1999 76<br />
Source<br />
Updated search<br />
Co-existent problems<br />
SNAP scale: ODD subscale (parents,<br />
teachers)<br />
Social Skills Rating System: social skills<br />
subscale (parents, teachers)<br />
Parent–child Relationship<br />
Questionnaire: 2 composite scales<br />
Abik<strong>of</strong>f Classroom Observational<br />
System: oppositional/aggressive<br />
symptoms<br />
Peer sociometric procedures: social<br />
skills, peer relations<br />
Videotaped parent–child interactions<br />
‘negative/ineffective discipline’ factor<br />
Arm 1<br />
Medication management<br />
28-day daily switch titration <strong>of</strong><br />
placebo, 5 mg MPH, 10 mg MPH,<br />
15 mg MPH or 20 mg MPH; full dose<br />
with breakfast <strong>and</strong> lunch, half dose in<br />
afternoon; best dose became<br />
subject’s initial maintenance dose; for<br />
non-responders to MPH, DEX, PEM,<br />
imipramine <strong>and</strong> approved o<strong>the</strong>r drugs<br />
subsequently titrated (in stated<br />
order); monthly maintenance visits<br />
with algorithmic dose adjustments;<br />
supplementary general advice <strong>and</strong><br />
biblio<strong>the</strong>rapy; case management by<br />
pharmaco<strong>the</strong>rapist; emergency<br />
services as needed<br />
(Individuals administering medication<br />
not reported)<br />
Setting<br />
USA<br />
Exclusion criteria<br />
(Limited to situations that would prevent families’ full participation in<br />
study, or might require additional treatment incompatible with study<br />
treatments)<br />
1. Child currently in hospital<br />
2. Child currently in ano<strong>the</strong>r study<br />
3.