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The Australian Immunisation Handbook 10th Edition 2013

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and males 9–26 years); use of HPV vaccine in males up to the age of 45 years<br />

is unlikely to be associated with immunogenicity or adverse events that differ<br />

from those observed in females. However, the benefit of HPV vaccination<br />

is optimal when delivered to children or young adolescents prior to sexual<br />

debut (see 4.6 Human papillomavirus).<br />

• Pneumococcal disease, both respiratory and invasive (IPD), is a frequent<br />

cause of morbidity in HIV-infected children and adults (see List 4.13.1 in<br />

4.13 Pneumococcal disease). 133 Children should be vaccinated initially with<br />

pneumococcal conjugate vaccine (13vPCV); the number of doses depends<br />

on age at diagnosis and vaccination history (see Table 2.1.11 Catch-up<br />

schedule for 13vPCV (Prevenar 13) and 23vPPV (Pneumovax 23) in children with<br />

a medical condition(s) associated with an increased risk of IPD, presenting at age<br />

5 years and adults, a single dose of 13vPCV<br />

is recommended, followed by 23vPPV; repeat doses of 23vPPV are also<br />

indicated. See 4.13 Pneumococcal disease for details.<br />

• Annual influenza vaccination is recommended in all HIV-infected<br />

adults and children (≥6 months of age). In HIV-infected persons who are<br />

immunocompromised and children

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