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The Australian Immunisation Handbook 10th Edition 2013

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Appendix 1 Contact details for <strong>Australian</strong>, state and territory government health<br />

authorities and communicable disease control).<br />

If a diagnosis of meningococcal disease is suspected, the patient should be<br />

immediately given parenteral (usually IM) penicillin and transferred to hospital.<br />

A potential outbreak of meningococcal disease in an institutional or community<br />

setting is a public health emergency needing a rapid response from clinicians<br />

and public health practitioners. <strong>The</strong> decision to control an outbreak with a<br />

vaccination program should be made by the appropriate Public Health Unit,<br />

following the Guidelines for the early clinical and public health management of<br />

meningococcal disease in Australia. 2<br />

4.10.12 Variations from product information<br />

<strong>The</strong> product information for meningococcal C conjugate vaccines states that,<br />

under the age of 12 months, either 2 (NeisVac-C) or 3 (Meningitec and Menjugate<br />

Syringe) doses of vaccine are required. <strong>The</strong> ATAGI recommends instead that<br />

meningococcal C vaccination is routinely not recommended before 12 months of<br />

age (unless specifically indicated).<br />

<strong>The</strong> product information for Meningitec states that an allergic reaction following<br />

a previous dose is a contraindication to further doses. <strong>The</strong> ATAGI recommends<br />

instead that the only contraindication is a history of anaphylaxis to a previous<br />

dose or to any of the vaccine components.<br />

<strong>The</strong> product information for NeisVac-C states that the vaccine should not be<br />

administered with pneumococcal conjugate vaccine, hepatitis B vaccine or<br />

PRP-OMP Haemophilus influenzae type b vaccine unless ‘medically important’.<br />

<strong>The</strong> ATAGI recommends instead that the vaccine may be administered<br />

simultaneously with other vaccines in the NIP. <strong>The</strong>re have been publications<br />

citing the co-administration of MenCCV with other combination vaccines and it<br />

was found to be immunogenic and safe. 57,58<br />

<strong>The</strong> product information for Menactra states that a previous episode of Guillain-<br />

Barré syndrome is a contraindication to vaccination with Menactra. <strong>The</strong> ATAGI<br />

recommends instead that either of the available 4vMenCVs can be administered.<br />

<strong>The</strong> product information for Menactra states that this vaccine is indicated for use<br />

in persons aged 2–55 years. <strong>The</strong> ATAGI recommends instead that Menactra can<br />

be given to persons aged ≥9 months of age.<br />

<strong>The</strong> product information for Menveo states that this vaccine is indicated for use<br />

in persons ≥11 years of age. <strong>The</strong> ATAGI recommends instead that Menveo can be<br />

given to persons aged ≥9 months of age.<br />

<strong>The</strong> product information for all meningococcal vaccines (MenCCV, 4vMenCV<br />

and 4vMenPV) states that there are no data on the use of these vaccines in<br />

lactating women. <strong>The</strong> ATAGI recommends that breastfeeding women can be<br />

vaccinated.<br />

PART 4 VACCINE-PREVENTABLE DISEASES 293<br />

4.10 MENINGOCOCCAL DISEASE

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